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ETHYL LACTYL RETINOATE.

Valuable CAS 74534-80-8 / ABRASIVE, SKIN CONDITIONING

Ethyl Lactyl Retinoate is an innovative double-conjugated molecule that uniquely combines a retinoid (retinoic acid) with an alpha hydroxy acid (lactic acid). This bioengineered compound is designed for enhanced stability and a time-released mechanism, delivering potent anti-aging and skin-renewing benefits with minimized irritation.

Anti-aging Exfoliation Acne Treatment Skin Brightening Collagen Boosting Skin Barrier Support

Science

This ingredient functions as a direct-acting retinoid, binding to retinoid receptors without requiring prior conversion to retinoic acid, akin to advanced retinoids like Granactive Retinoid. It actively promotes rapid cell turnover, boosts collagen and elastin production, and thickens the dermis, thereby visibly reducing the appearance of fine lines and wrinkles. Concurrently, its lactic acid component provides gentle exfoliation, effectively removing dead skin cells to reveal a brighter, more even skin tone. The hydrolysis-based time-released delivery system optimizes both efficacy and skin tolerance, contributing to a more robust and compact skin barrier.


Research

Medium confidence
Effective range 0.1–0.1%
Optimal

0.1%

Key findings

  1. 01 In an 8-week clinical study, an anti-aging serum containing 0.1% Ethyl Lactyl Retinoate significantly improved photodamage, dryness/flaking, dyschromia, and overall global appearance in women with moderate-to-severe photodamage.
  2. 02 An 8-week clinical trial involving 27 subjects with mild to moderate acne demonstrated a significant reduction in inflammatory and non-inflammatory lesions after 4 weeks, with continued improvement at 8 weeks, when using a twice-daily serum containing 0.1% Ethyl Lactyl Retinoate.

Transparency

Not commonly dusted

Insufficient data available to determine if Ethyl Lactyl Retinoate is commonly 'dusted' in formulations below effective concentrations.


The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Ethyl Lactyl Retinoate is engineered for superior stability compared to conventional retinoids like retinol, exhibiting greater resilience to degradation from light and air. Its bioengineered, hydrolysis-based time-released mechanism further contributes to its sustained potency and minimizes potential irritation in formulations.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While specific CIR, SCCS, or FDA safety assessments for Ethyl Lactyl Retinoate as a standalone ingredient are not documented, clinical studies indicate it is a safe and effective topical therapy for concerns such as moderate-to-severe photodamage. No data is available regarding pregnancy safety.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Ethyl Lactyl Retinoate is a valuable ingredient, effectively addressing multiple skin concerns like photodamage, aging, and acne, while its enhanced stability and low irritation profile make it a well-tolerated and potent option for skin renewal.


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