Science
Mechanism of Action
Ethyl Ester of Hydrolyzed Silk operates through multiple pathways to rejuvenate the skin. It acts as a potent antioxidant, neutralizing oxidative stress and safeguarding cells from damage, partly by upregulating cellular defense proteins like bcl-2. This ingredient actively promotes cellular repair and protects against UV radiation. Its anti-aging efficacy stems from stimulating Type I collagen synthesis, providing crucial amino acid building blocks, and enhancing overall skin structural integrity, leading to improved hydration and a refined dermal surface.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 General 'silk protein treatments' have demonstrated a 7.3% reduction in wrinkle depth measurements over 56 days, with improvements linked to enhanced hydration, collagen synthesis, and dermal structure. These silk-based formulations also show 20-30% higher moisturizing effects compared to hyaluronic acid and glycerin.
- 02 Formulations specifically incorporating Ethyl Ester of Hydrolyzed Silk have exhibited good physicochemical stability, including stable pH and consistent viscosity, and in vivo evaluations reported no significant adverse effects or skin reactions (erythema or edema) across test populations.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The ethyl ester of hydrolyzed silk is completely soluble in alcohol, enhancing its versatility in alcohol-based formulations and improving interaction with other cosmetic ingredients. Formulations containing this ingredient have demonstrated good physicochemical stability, maintaining stable pH and viscosity over time.
Safety
Safety Profile
While the CIR Expert Panel has reviewed other silk protein ingredients, Ethyl Ester of Hydrolyzed Silk itself has not been individually assessed. However, it is rated 'LOW' by EWG for concerns such as cancer, allergies & immunotoxicity, and developmental & reproductive toxicity. In silico assessments and in vivo evaluations of formulations containing the ingredient indicate no mutagenic/sensitizing alerts and no significant adverse skin reactions.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ethyl Ester of Hydrolyzed Silk is a valuable, multi-functional ingredient providing notable anti-aging, antioxidant, and moisturizing benefits with an excellent safety profile.
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