Science
Mechanism of Action
This extract operates on multiple biological pathways to rejuvenate skin. Rich in antioxidants like phenolic acids and flavonols, it effectively scavenges free radicals, mitigating oxidative stress and cellular damage. It promotes deep hydration by significantly increasing AQP3 gene expression, crucial for water transport within skin cells, while boosting TERT gene expression to support cellular longevity. By specifically targeting the Epidermal-Dermal Junction, it stimulates the synthesis of essential structural proteins like elastin and collagen, thereby improving skin density, firmness, and elasticity. Furthermore, the extract's exosomes can activate human skin cells, leading to increased collagen production, reduced inflammation, enhanced barrier resilience, and a soothing effect on redness and warmth.
Research
Clinical Evidence
High confidenceFor anti-aging and hydration, 1% was found highly effective in vitro, significantly increasing TERT and AQP3 gene expression. For antioxidant activity (DPPH scavenging), concentrations of 5% and 10% demonstrated significant results in in vitro assays.
Key findings
- 01 In vitro experiments at 1% concentration demonstrated significant anti-aging and hydration effects, specifically increasing expression of TERT and AQP3 genes.
- 02 In vitro assays showed significant DPPH scavenging activity (antioxidant properties) at 5% and 10% concentrations.
- 03 Clinical trials on human participants with a multilayered liposome-encapsulated formulation (Cellbiome) significantly improved skin density, moisturization, and elasticity, leading to visible wrinkle reduction and overall skin health.
Transparency
Dusting Analysis
Effective concentrations for Eryngium Maritimum Extract have been observed at 1% for cellular regeneration and hydration, and 5-10% for antioxidant benefits in in vitro settings. Human clinical trials demonstrate efficacy in a final product formulation. These active percentages suggest it's typically used at levels that provide tangible benefits, making it less prone to being 'dusted' at sub-efficacious concentrations.
The Formula
Formulation
Stability
This extract is water-soluble. Encapsulation in multilayered liposomes, including exosome forms, significantly enhances its stability and improves absorption, facilitating more efficient delivery to deeper skin layers. The callus culture medium used in its production was adjusted to pH 5.8, suggesting good stability around this mildly acidic range.
Safety
Safety Profile
Eryngium Maritimum Callus Culture Filtrate is generally considered safe for cosmetic use, with null cytotoxicity observed in Jurkat cells. While the overall risk is low, individuals with sensitive skin or a history of allergies are advised to perform a patch test before initial use to confirm personal tolerance. Regulatory authorities like the European Cosmetics Regulation approve its use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Eryngium Maritimum Extract is a valuable, evidence-backed ingredient that deeply rejuvenates skin by enhancing hydration, stimulating collagen and elastin, and providing robust antioxidant protection for diverse skin types.
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