Science
Mechanism of Action
This extract operates through multiple advanced pathways to support skin health. Rich in antioxidants, it actively scavenges free radicals, thereby mitigating oxidative damage and signs of photoaging. It precisely targets the Epidermal-Dermal Junction, enhancing the synthesis of structural proteins like collagen and elastin, crucial for firmness and elasticity. Furthermore, it stimulates epidermal cell proliferation and glycosaminoglycan (GAG) production, leading to improved skin density, hydration, and overall renewal. When delivered via plant exosomes, it facilitates intercellular communication, further boosting collagen production, reducing inflammation, and strengthening the skin barrier function for comprehensive repair and regeneration.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Studies indicate a 15% increase in collagen and 16% in GAGs, coupled with a 19% stimulation of epidermal mitotic index.
- 02 In vitro, this range significantly promoted keratinocyte cell proliferation, aiding in skin renewal.
- 03 Demonstrated substantial free radical scavenging and antioxidant activity in vitro.
- 04 Recommended dosage for commercial exosomal products of the callus culture filtrate.
- 05 A liposome-encapsulated formulation containing the extract notably improved skin density, hydration, elasticity, and reduced wrinkles in human clinical trials.
Transparency
Dusting Analysis
Given established effective concentrations as low as 0.01% in commercial exosomal formulations and demonstrable benefits at 0.05% for collagen and GAG production, this ingredient is typically utilized at levels designed for efficacy rather than mere label claims.
The Formula
Formulation
Stability
This ingredient is water-soluble, available as a liquid or lyophilized powder, and integrates seamlessly into diverse cosmetic formulations. Encapsulation within liposomes can significantly enhance its stability and improve absorption into the skin. The original callus culture medium was maintained at pH 5.8.
Safety
Safety Profile
Eryngium Maritimum Callus Culture Extract is generally recognized as safe for cosmetic applications, with regulatory approval in regions such as the EU. While considered low risk, individuals with highly sensitive skin or known allergies should perform a patch test prior to widespread use. The EWG Skin Deep database indicates low concerns for related Eryngium Maritimum extracts regarding cancer, allergies, immunotoxicity, and developmental and reproductive toxicity.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Eryngium Maritimum Callus Culture Extract is a valuable, multi-functional active ingredient that effectively addresses signs of aging, promotes skin regeneration, and offers comprehensive environmental protection across all skin types.
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References
Sources