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Moumoujus

ERUCA SATIVA LEAF EXTRACT.

Valuable CAS 90028-42-5 / SKIN CONDITIONING

Eruca Sativa Leaf Extract is a multi-functional botanical ingredient recognized for its potent antioxidant, anti-inflammatory, and barrier-supporting properties. Sourced from the arugula plant, it actively defends skin from environmental stressors and enhances skin resilience across all skin types.

Summary

skin conditioning antioxidant anti-inflammatory skin barrier support antimicrobial

Science

Mechanism of Action

This extract is rich in potent antioxidants, including a complex blend of flavonoids, phenolics, and glucosinolates, which collectively neutralize free radicals, decompose peroxides, and chelate metal ions such as Fe2+ to protect skin from oxidative damage. It provides anti-inflammatory benefits by stimulating peroxisome proliferator-activated receptor (PPAR)-α and reducing pro-inflammatory cytokines like IL-6 and TNF-α, alongside decreasing nitric oxide. Furthermore, Eruca Sativa Leaf Extract reinforces the skin barrier through the promotion of keratinocyte differentiation and increased expression of filaggrin, a critical protein for epidermal integrity. Its bioactive compounds, including erucic acid and isothiocyanates, also impart antimicrobial activity.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 In vitro assessments demonstrated robust antioxidant capabilities, including scavenging radicals, breaking down peroxides, and chelating Fe2+. The extract and its glucosinolate fraction exhibited notable cytoprotective effects and reduced intracellular reactive oxygen species production in human peripheral blood mononuclear cells.
  2. 02 Studies indicated an improvement in skin barrier function through the activation of peroxisome proliferator-activated receptor (PPAR)-α and suppression of inflammatory cytokines. It also enhanced the expression of filaggrin.
  3. 03 When tested at 75 mg/ml, in conjunction with 1.5 mg/L brassinolide, the extract inhibited the bacterial growth of Staphylococcus aureus isolates in vitro.

Transparency

Dusting Analysis

Not commonly dusted

No data suggests Eruca Sativa Leaf Extract is commonly used at ineffective 'dusting' concentrations, nor are there specified thresholds for such practices.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

A key flavonoid component, kaempferol-3,4′-di-O-β-glucoside, displayed significantly greater stability in acidic conditions (11.5% degradation) compared to alkaline conditions (46.6% degradation), suggesting optimal performance in lower pH environments. It is commonly dissolved in a base of glycerin and water.

Synergies

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Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Generally regarded as a non-irritating ingredient suitable for most skin concerns. SkinSAFE categorizes it as 'Irritant Free', 'Teen SAFE', 'Lip SAFE', 'Baby SAFE', and 'Eyelid SAFE'. While highly tolerable, caution is advised as irritation risk may increase when formulated with other known problematic ingredients. Official regulatory assessments (CIR, SCCS, FDA) and specific maximum concentrations are not currently available in the research data.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Eruca Sativa Leaf Extract is a valuable, multi-beneficial ingredient offering comprehensive protection, anti-inflammatory effects, and barrier support, making it suitable for all skin types with a low risk of irritation.

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