Science
Mechanism of Action
The mechanism of this combined extract is rooted in the synergistic actions of its botanical components. Eriobotrya japonica leaf extract (EJLE) demonstrates significant antioxidant activity through free radical scavenging and superoxide dismutase-like mechanisms. Its anti-inflammatory properties arise from the inhibition of inflammatory mediators such as NO, iNOS, COX-2, TNF-α, and IL-6, coupled with modulation of the NF-κB and MAPK pathways. EJLE also curbs melanogenesis by inhibiting tyrosinase activity. Furthermore, triterpenoids within EJLE contribute to anti-acne, anti-allergy, and anti-aging effects by impeding collagenase and hyaluronidase, crucial enzymes for maintaining skin elasticity and hydration. Taraxacum officinale extract, utilized as a representative for Taraxacum platycarpum, complements these effects by offering additional antioxidant support, soothing irritated skin, brightening the complexion through hyperpigmentation reduction, and protecting skin cells from UVB-induced damage by minimizing reactive oxygen species and matrix metalloproteinase activities. Both components collectively enhance skin conditioning and protective functions.
Research
Clinical Evidence
Medium confidence0.5%
Key findings
- 01 Inhibition of NO and TNF-α production (anti-inflammatory) and melanogenesis (anti-melanogenic) in cell models (RAW 264.7 macrophage and B16F1 cells). No skin or eye irritation observed in animal alternative tests.
- 02 Demonstrated significant in vitro antioxidant activity (DPPH and ABTS radical scavenging, superoxide dismutase-like activity).
- 03 Exhibited anti-melanogenesis, anti-acne, anti-allergy, and anti-aging activities (inhibiting collagenase and hyaluronidase).
- 04 Led to a slight reduction in acne severity without adverse effects and protected skin fibroblasts from UVB radiation damage by reducing reactive oxygen species and matrix metalloproteinase activities.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Both Eriobotrya japonica leaf extract and Taraxacum officinale extract are typically prepared as water or ethanol extracts, indicating good dispersibility or solubility in aqueous systems. Specific optimal pH ranges for the stability of the combined extract in formulations are not extensively documented.
Safety
Safety Profile
Eriobotrya japonica leaf extract has shown no toxicity or irritation at 0.5% (w/v) in animal alternative tests. It is generally rated 'LOW' by EWG for various concerns. Taraxacum officinale extract is widely considered safe, non-toxic, non-sensitizing, and non-comedogenic, with the European Union Cosmetics Regulation recognizing its safety. However, rare instances of skin irritation may occur in individuals with allergies to plants of the Asteraceae family. Specific comprehensive safety assessments for the combined extract have not been identified.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This potent botanical complex offers comprehensive dermal support, demonstrating robust antioxidant and anti-inflammatory actions alongside benefits for skin clarity, aging, and environmental protection with a low irritation profile.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources