Science
Mechanism of Action
This complex extract operates through a combination of its individual botanical constituents. Eriobotrya Japonica Leaf Extract provides anti-inflammatory, antioxidant, and anti-melanogenic properties, primarily due to phytochemicals such as quercetin, ursolic acid, oleanolic acid, tannin, chlorogenic acid, and caffeoylquinic acid. These compounds effectively scavenge free radicals, inhibit inflammatory cytokine production, and modulate the MAPK signaling pathway. Houttuynia Cordata Leaf/Stem Extract further contributes with anti-inflammatory, antioxidant, and antibacterial activities, enhancing protection against UVB-induced damage through its rich content of polyphenolic flavonoids like quercetin, quercitrin, hyperoside, and rutin, alongside beneficial polysaccharides. Related species to Sophora Flavescens are also recognized for their skin conditioning and protective attributes.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 An ethanol extract of Eriobotrya japonica leaf (EJEE) at 0.5% (w/v) demonstrated significant anti-inflammatory, anti-oxidant, and anti-melanogenic activities in in vitro models. Concurrently, it did not induce skin or eye irritation in animal alternative tests, suggesting its potential for cosmetic applications.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Eriobotrya japonica leaf ethanol extract did not demonstrate skin or eye irritation in animal alternative tests at a 0.5% (w/v) concentration. A 13-week oral subchronic toxicity study in rats found no observed adverse effects for Eriobotrya japonica leaf extract at doses up to 1000 mg/kg/day. However, no specific Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA status has been established for the entire complex blend in a topical application context.
Your Skin
Skin Compatibility
Our Assessment
Verdict
This complex botanical extract is a valuable ingredient, offering proven anti-inflammatory, antioxidant, and anti-melanogenic benefits with demonstrated low irritation potential for its key components, making it ideal for soothing, brightening, and protecting the skin.
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References
Sources