Science
Mechanism of Action
This extract functions via a rich profile of phenolic acids, flavonoids, and triterpenes. It neutralizes oxidative stress by scavenging free radicals and reduces inflammation through the suppression of nitric oxide and TNF-α production, alongside modulating key signaling pathways like MAPK and NF-κB. Additionally, it inhibits melanin synthesis for a brightening effect, and its anti-aging properties stem from hindering collagenase and hyaluronidase activity, thereby preserving collagen and hyaluronic acid to maintain skin structure and hydration. The extract also possesses antimicrobial properties.
Research
Clinical Evidence
High confidence0.5%
Key findings
- 01 Demonstrated significant antioxidant activity, achieving an 86% DPPH free radical scavenging capacity.
- 02 Exhibited anti-inflammatory effects by reducing lipopolysaccharide-induced nitric oxide and tumor necrosis factor-alpha levels.
- 03 Specific triterpenoids (ursolic, maslinic, corosolic, and euscaphic acids) from loquat leaves showed anti-acne activity against P. acnes, with Minimum Inhibitory Concentrations (MIC) of 50 µg/mL and Minimum Bactericidal Concentrations (MBC) from 50 to 150 µg/mL.
- 04 Key triterpenoids significantly suppressed β-hexosaminidase release, indicating anti-allergy activity (ursolic acid 72.5%, euscaphic acid 74.5%, maslinic acid 66% suppression).
- 05 Triterpenoids from the leaves were observed to restore collagen synthesis (3- to 4-fold increase) and hyaluronic acid synthesis (5- to 6-fold increase).
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Challenges exist regarding the stability of key functional components in processed products, and some deep eutectic solvents used for extraction may be unstable under high temperatures or specific conditions.
Safety
Safety Profile
Eriobotrya japonica leaf ethanol extract was evaluated in animal alternative tests and deemed a non-irritant, posing no risk of skin or eye irritation.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Eriobotrya Japonica Fruit/Leaf Extract is a valuable botanical active offering extensive benefits including antioxidant, anti-inflammatory, anti-acne, anti-allergy, and anti-aging properties, making it suitable for a wide range of skin concerns with a low irritancy risk.
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References
Sources