Science
Mechanism of Action
This extract contains silica, a key structural component crucial for the biosynthesis of collagen, thereby contributing to improved skin elasticity and firmness. It exhibits antimicrobial capabilities, effectively inhibiting the growth of bacteria such as Staphylococcus aureus and Escherichia coli, which supports a healthy skin microbiome and aids in wound cleanliness. Furthermore, the extract possesses anti-inflammatory properties, modulating cytokine secretion by increasing IL-10 release and inhibiting MCP-1, IFN-γ, and TNF-α, which can help calm irritation and mitigate symptoms of inflammatory skin conditions. Its robust antioxidant profile provides protection against environmental stressors, promoting overall skin resilience.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Accelerated wound healing in diabetic rats by increasing fibroblast collagen synthesis, modulating IL-10 and MCP-1 release, and inhibiting the growth of Staphylococcus aureus and Escherichia coli.
- 02 Exhibited hair-regenerative properties with high tensile strengths, combined masses, and follicular growth in chemically-induced alopecia in rats, indicating topical biological activity.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has not specifically reviewed Equisetum hyemale Leaf/Stem Extract. However, related species like Equisetum arvense-derived ingredients were found safe for cosmetic use, with Equisetum arvense extract used up to 0.4% in leave-on products. For topical Equisetum hyemale, there is currently insufficient reliable information to definitively assess its safety or potential side effects. Ingesting high concentrations of raw plant material is not recommended due to elevated thiaminase levels.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Equisetum hyemale Leaf/Stem Extract is a valuable botanical active, showcasing promising antioxidant, anti-inflammatory, and collagen-supportive properties in preclinical studies, making it beneficial for promoting overall skin vitality and repair.
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