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Moumoujus

ELETTARIA CARDAMOMUM SEED OIL.

Valuable CAS 8000-66-6 / 85940-32-5 / FRAGRANCE, PERFUMING, TONIC

Derived from the seeds of the cardamom plant, Elettaria Cardamomum Seed Oil is a potent essential oil celebrated for its diverse benefits. Rich in bioactive compounds, it is recognized for its antioxidant, anti-inflammatory, and antimicrobial properties, making it a multifaceted ingredient for skin health.

Summary

antioxidant anti-inflammatory antimicrobial masking perfuming tonic

Science

Mechanism of Action

This seed oil's efficacy is attributed to its complex profile of flavonoids, polyphenols, terpenes, and essential fatty acids, notably eucalyptol. It functions as a robust antioxidant, actively neutralizing free radicals and protecting skin cells from environmental damage. Its anti-inflammatory mechanism involves the concentration-dependent inhibition of vascular cell adhesion molecule 1 (VCAM-1) and macrophage colony-stimulating factor (M-CSF) expression in human dermal fibroblasts. Furthermore, it modulates inflammatory pathways by reducing pro-inflammatory gene expression (e.g., NFkβ, TNFα, IL-6, COX2) and enhancing nuclear receptors LXRα and PPARγ. It also exhibits antimicrobial activity against acne-causing bacteria and can support improved microcirculation, contributing to a more even skin tone.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Cardamom essential oil (CEO) demonstrated concentration-dependent inhibition of human dermal fibroblast proliferation and significantly suppressed the expression of VCAM-1 and M-CSF, indicating potent anti-inflammatory and immunomodulatory potential.
  2. 02 An Elettaria cardamomum extract, at concentrations with an EC50 higher than 321.20 µg/mL, exhibited anti-inflammatory effects by lowering pro-inflammatory gene expression (NFkβ, TNFα, IL-6, COX2) and reducing reactive oxygen species in cellular models.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The oil itself presents a neutral pH. During stability testing, esters within the oil can hydrolyze to form corresponding acids. Terpenes, naturally occurring components in the raw material, are susceptible to polymerization upon oxidation, which can impact product stability and efficacy.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

Elettaria Cardamomum Seed Oil is generally considered safe for use in cosmetics when properly diluted. As an essential oil, undiluted or high concentrations can lead to skin sensitivity, irritation, or an allergic skin reaction; patch testing is strongly recommended prior to extensive use. It has been reported to cause serious eye irritation. While the FDA lists it as Generally Recognized As Safe (GRAS) for food use, the Cosmetic Ingredient Review (CIR) has not evaluated it. Furthermore, EWG restricts its use in EWG VERIFIED products due to documented concerns regarding skin allergies and irritation.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Elettaria Cardamomum Seed Oil offers valuable antioxidant, anti-inflammatory, and antimicrobial benefits for skin, but its use requires precise formulation and significant dilution to mitigate potential irritation or sensitization risks.

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