Science
Mechanism of Action
This extract operates via a broad spectrum of biological activities on the skin. Its beneficial effects stem from a rich profile of phytochemical compounds, including flavonoids, tannins, and triterpenoids. These constituents contribute to its demonstrated antibacterial, antifungal, anti-inflammatory, and antioxidant capabilities, supporting overall skin health and resilience.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 In in vitro and animal studies, the extract exhibited 79.2% efficacy in antibacterial analysis.
- 02 Further in vitro and animal research showed an 83.55% inhibition of inflammatory markers.
- 03 An in vitro study demonstrated significant antimicrobial action specifically against Propionibacterium acnes, a bacterium associated with acne.
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
Acute and subacute toxicity assessments in animal studies of the root extract showed no mortality at doses up to 5000 mg/kg body weight, with insignificant nephrotoxic and hepatocellular adverse effects. However, it is crucial to distinguish that while the root extract appears safe, the seeds of E. elephantina are reported to be strongly irritant.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Elephantorrhiza elephantina Root Extract presents as a valuable ingredient with promising antibacterial, anti-inflammatory, and antioxidant benefits, supported by traditional use and initial in vitro/animal studies, though further human clinical research is needed for topical application.
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References
Sources