Science
Mechanism of Action
This extract, drawing insights from the broader Elaeagnus genus, is postulated to operate via several mechanisms on the skin. Its high content of polyphenols, flavonoids, and carotenoids likely contributes to antioxidant effects by mitigating oxidative stress and inhibiting superoxide anion production. Anti-inflammatory actions may involve alleviating the infiltration of inflammatory cells. Furthermore, based on related species, it could promote wound healing by enhancing fibroblast migration and upregulating key genes such as VEGF-A, HLA-G5, and IL-6. Anti-photoaging benefits might stem from restoring type I collagen and hyaluronan through the inhibition of matrix metalloproteinases and p38 mitogen-activated protein kinase expression. Additionally, certain Elaeagnus species have shown potential whitening effects by inhibiting tyrosinase activity and melanin biosynthesis.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Specific topical clinical efficacy with defined effective concentrations for ELAEAGNUS GLABRA FRUIT EXTRACT itself is not yet available. However, studies on related Elaeagnus species demonstrate biological activities. For instance, Elaeagnus angustifolia extract at a nontoxic concentration of 100 µg/ml in vitro improved human dermal fibroblast migration and significantly increased wound healing-related genes (VEGF-A, HLA-G5, IL-6). Elaeagnus multiflora extract demonstrated complete inhibition of tyrosinase activity at 30 µg/ml and over 90% inhibition of melanin biosynthesis at 3 µg/ml in B16BL6 mouse melanoma cells. Oral administration of Elaeagnus umbellata fruit extract (50–200 mg/kg daily for 15 weeks) in hairless mice prevented UV-mediated photoaging.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Specific optimal pH range and stability notes for ELAEAGNUS GLABRA FRUIT EXTRACT are not readily available. However, fruit extracts, especially those rich in phenolic compounds and polysaccharides, are typically water-soluble, and their stability can be influenced by pH, temperature, and light.
Safety
Safety Profile
No specific safety assessments by major regulatory bodies such as CIR (Cosmetic Ingredient Review), SCCS (Scientific Committee on Consumer Safety), or FDA are currently available for ELAEAGNUS GLABRA FRUIT EXTRACT. Cosmetic ingredient databases list it as a skin conditioning agent but indicate no available safety data or references.
Your Skin
Skin Compatibility
Our Assessment
Verdict
While studies on related Elaeagnus species indicate promising antioxidant, anti-inflammatory, and regenerative skin benefits at specific concentrations, comprehensive clinical efficacy and safety data for topical ELAEAGNUS GLABRA FRUIT EXTRACT itself are currently insufficient for a definitive assessment.
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