Science
Mechanism of Action
Eclipta Prostrata Leaf Oil exerts its effects through a rich profile of bioactive compounds, notably flavonoids and coumestans. These constituents function as powerful antioxidants, actively neutralizing free radicals to shield skin from environmental damage and mitigate premature aging. Its anti-inflammatory capabilities reduce redness, swelling, and irritation. The oil also supports skin regeneration, potentially enhancing elasticity and stimulating collagen synthesis, which contributes to firmer skin and a refined appearance of fine lines. Furthermore, it delivers moisturizing benefits and exhibits broad-spectrum antimicrobial activity, making it effective against various skin concerns.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Eclipta prostrata extract demonstrated antibacterial effects, inhibiting bacterial growth at concentrations ranging from 1000-1200 mg/l.
- 02 A 1400 mg/l concentration of Eclipta prostrata extract effectively inhibited fungal growth.
- 03 In animal studies, a hair oil formulation containing Eclipta prostrata resulted in a mean hair length of 4.6 mm, outperforming minoxidil. It significantly increased anagen phase follicles to 82%, compared to 67% in the standard control group.
- 04 Eclipta prostrata extract showed significant reducing ability, with an IC50 value of 100 µg/mL and achieving its highest reducing ability (75.59%) at 250 µg/mL.
- 05 Butanol and water extracts of Eclipta prostrata, at 3 mg/disc, inhibited the growth of Bacillus cereus by 45% and 42% respectively.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
While specifically referring to the extract, an optimal pH range of 4.5-6.5 provides a general guideline for Eclipta Prostrata formulations. Formulators must ensure precise dilution and compatibility with other ingredients to maintain the product's stability and maximize efficacy.
Safety
Safety Profile
Eclipta Prostrata Extract, a closely related compound, is generally considered safe, non-toxic, and well-tolerated for topical use across most skin types, and is noted as non-comedogenic. However, due to potential individual sensitivities, particularly for individuals with known allergies to plants within the Asteraceae family, a patch test prior to full application is recommended. Research suggesting liver toxicity in mice at high oral doses is not directly extrapolatable to topical skincare concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Eclipta Prostrata Leaf Oil is a valuable botanical ingredient, offering diverse benefits including antioxidant protection, anti-inflammatory action, and regenerative properties, making it beneficial for both skin health and hair vitality.
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