Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle
Moumoujus

ECHINACEA ANGUSTIFOLIA CELL CULTURE EXTRACT.

Valuable CAS 84696-11-7 / ANTIOXIDANT, SKIN PROTECTING

Echinacea Angustifolia Cell Culture Extract is a botanical active derived from the controlled cultivation of Echinacea angustifolia plant cells. This precision ingredient is engineered to deliver comprehensive dermal benefits, ranging from enhanced hydration and anti-aging effects to potent skin soothing and barrier support.

Summary

Antioxidant Anti-inflammatory Immunomodulatory Collagen Production Booster Hyaluronic Acid Production Booster Skin Hydration Enhancer Elasticity Improvement Wrinkle Care Skin Barrier Support Wound Healing Skin Soothing

Science

Mechanism of Action

This extract operates through multiple pathways to optimize skin health. It exhibits robust antioxidant capabilities, effectively neutralizing free radicals to mitigate photo-aging effects. Its anti-inflammatory and immunomodulatory properties work to calm irritation and strengthen the skin's natural defense mechanisms. Furthermore, it actively promotes the biosynthesis of vital extracellular matrix components, specifically collagen and hyaluronic acid, which leads to improved skin elasticity, enhanced moisturization, and visible reduction in wrinkles. It also reinforces the skin's protective lipid barrier, accelerates wound healing through increased cellular migration and reduced pro-inflammatory cytokines, and inhibits hyaluronidase, an enzyme that degrades hyaluronic acid.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Echinacea angustifolia cell culture extract demonstrated clear improvements in both hyaluronic acid and collagen production, contributing to enhanced skin moisturizing and wrinkle care.
  2. 02 A hydroalcoholic extract of E. angustifolia root significantly enhanced cell proliferation rate, increasing it approximately threefold compared to control, while lower concentrations (5–100 μg/mL) did not stimulate proliferation.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Extensive in vitro and in vivo assessments have shown no genotoxicity, and acute toxicity studies in rodents with E. angustifolia DC extract indicated no signs of toxicity or mortality at doses up to 2,000 mg/kg. Echinacoside, a primary bioactive component, has been confirmed safe and non-toxic within the concentration range of 0.01–0.50 mM, with no observed cytotoxic effects on 3T3-L1 cells. Echinacoside derived from E. angustifolia cell cultures is also recognized as a Novel Food certified ingredient, further underscoring its safety profile for internal consumption.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Echinacea Angustifolia Cell Culture Extract is a valuable, multifaceted ingredient that offers significant benefits for anti-aging, hydration, soothing, and skin barrier health, demonstrating a robust safety and broad skin type compatibility profile.

Related

Similar Ingredients

Finding similar ingredients…