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Moumoujus

DURIO ZIBETHINUS FRUIT EXTRACT.

Valuable CAS 93165-21-0 / SKIN CONDITIONING

Durio Zibethinus Fruit Extract is a multi-functional botanical ingredient recognized for its comprehensive dermatological benefits. This extract brightens and evens skin tone, provides significant antioxidant protection, and delivers essential hydration for a healthier, more resilient complexion. It also offers photoprotective and anti-aging properties.

Summary

Antioxidant Brightening Moisturizing Anti-inflammatory Anti-aging Photoprotective Skin Conditioning

Science

Mechanism of Action

This fruit extract acts as a potent antioxidant by actively neutralizing free radicals, thereby protecting skin cells from oxidative stress and environmental damage. It exhibits anti-tyrosinase activity, which contributes to skin brightening and evening skin tone by inhibiting melanogenesis. Polysaccharide components within the extract contribute to its moisturizing efficacy. Furthermore, it possesses anti-inflammatory properties and mitigates Matrix Metalloprotease (MMP) induction, crucial for preserving collagen and elastin integrity, thus supporting skin firmness and reducing signs of aging.

Research

Clinical Evidence

Medium confidence
Effective range 0.01–0.1%
Optimal

N/A

Key findings

  1. 01 Gel formulations containing 0.65% durian extract demonstrated skin safety, with no irritation or allergic reactions reported by volunteers, alongside observed moisturizing effects.
  2. 02 A combined extract exhibited anti-tyrosinase activity with an IC50 of 0.067 mg/mL, an efficacy comparable to kojic acid, suggesting significant potential for skin brightening.
  3. 03 Durian seed extract showed robust antioxidant activity via DPPH radical scavenging, evidenced by an IC50 of 0.08 mg/mL.
  4. 04 Durian peel extract displayed photoprotective capabilities, with concentrations from 0.01% to 0.1% (100-1000 ppm) yielding SPF values ranging from 4.40 to 16.85, demonstrating a concentration-dependent increase in protection.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Ethanolic crude extracts (pulp and seed) may exhibit color and odor changes at pH 8. Polysaccharide extracts from fruit-hulls can show color changes to brown at pH 7 and 8, with viscosity decreasing as pH values rise between 6 and 8. Optimal stability for gel formulations has been observed around pH 5.96 ± 0.47, indicating a preferred acidic to slightly acidic range of pH 4.0-7.0.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Patch tests on human volunteers indicate formulations containing Durio Zibethinus Fruit Extract are well-tolerated, with no reports of skin irritation or allergic reactions, suggesting a low sensitization risk and safety for cosmetic use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Durio Zibethinus Fruit Extract is a valuable, multi-functional ingredient providing robust antioxidant protection, skin brightening, hydration, and anti-aging benefits, making it suitable for a diverse array of skin types and cosmetic applications.

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