Science
Mechanism of Action
This botanical extract functions by scavenging free radicals and inhibiting lipid peroxidation through the action of polyphenolic compounds, including flavonoids and phenols, thereby providing antioxidant defense. Furthermore, it demonstrates antimicrobial efficacy against various fungi and bacteria, with preliminary indications of anti-inflammatory potential.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
No specific data available to determine dusting prevalence or thresholds for this ingredient.
The Formula
Formulation
Stability
Specific optimal pH and stability data are not extensively documented.
Safety
Safety Profile
While an oral LD50 greater than 5000 mg/kg suggests low acute oral toxicity for some extracts, the fruit of Duranta repens is recognized as poisonous when ingested, having caused reported fatalities due to alkaloids and hydrocyanic acid. Animal studies have linked chloroform-soluble stem fractions to liver and renal dysfunction. Critical specific safety assessments for cosmetic topical application are currently unavailable, advising caution in its use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Duranta repens extract demonstrates promising in vitro antioxidant and antifungal properties, but a critical lack of specific safety assessments and in-vivo efficacy studies for topical cosmetic use restricts its current recommendation.
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References
Sources