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DUNALIELLA SALINA EXTRACT.

Valuable / SKIN CONDITIONING

Dunaliella Salina Extract, derived from a unique micro-algae, is a multi-functional ingredient rich in carotenoids and essential nutrients. It precisely targets key markers of skin aging and environmental damage, offering potent antioxidant, anti-inflammatory, and anti-glycation benefits while enhancing skin resilience and hydration.

Summary

Antioxidant Anti-inflammatory Anti-glycation Skin-Conditioning Humectant Photoprotective Hyperpigmentation Reduction Collagen Support Skin Renewal

Science

Mechanism of Action

This extract operates through several distinct pathways: it leverages colorless carotenoids (phytoene, phytofluene) and beta-carotene to neutralize free radicals, reverse oxidative damage, and absorb UVA/UVB rays. Its antiglycation properties reduce the formation of advanced glycation end products (AGEs) and their receptors. Furthermore, it modulates the immune response by significantly decreasing inflammatory interleukins IL-6 (by 26%) and IL-8 (by 45%) and upregulating NRF2 (by 19%), a critical regulator of antioxidant and anti-inflammatory processes, which helps soothe sensitive or inflamed skin. The presence of glycerol, minerals, amino acids, fatty acids, proteins, and vitamins (E and B) also contributes to robust skin conditioning, moisture maintenance, and cellular renewal.

Research

Clinical Evidence

High confidence
Effective range 0.5–1%
Optimal

1%

Key findings

  1. 01 In vitro studies applying 0.5% Dunaliella Salina Extract to skin explants for 24 hours demonstrated a significant reduction in inflammatory interleukins IL-6 (by 26%) and IL-8 (by 45%), alongside a 19% enhancement of the key antioxidant and anti-inflammatory regulator NRF2.
  2. 02 A 56-day placebo-controlled clinical trial utilized a 1% Dunaliella Salina Extract formulation under intense solar exposure. Results showed a reduction in glycation scores, strengthened skin resilience against irritation, mitigated inflammation, and significantly decreased skin redness and wrinkles compared to placebo.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 3.5 – 5.5
0 7 14

Stability

The carotenoid components are sensitive to oxidation when exposed to air (oxygen) and light, requiring storage in a cool, dry, and light-protected environment for optimal stability. Solubility can vary; micro-algae extracts are often water-soluble, while beta-carotene-rich forms may be oil-soluble, and phytoene/phytofluene-rich extracts are hydrophobic. An aqueous extract typically exhibits a pH between 3.5 and 4.5, with commercially available micro-algae extracts ranging from 4.5-5.5 pH.

Safety

Safety Profile

CIR Status
Insufficient data
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has noted 'Insufficient Data' for red algae-derived ingredients, requesting additional information such as composition, a 28-day dermal toxicity assay, and dermal sensitization data. However, based on General Harmonized System (GHS) classification, Dunaliella Salina Extract is not categorized as a dangerous substance and presents 'no known hazard' for skin contact, generally being considered safe with low irritancy.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Dunaliella Salina Extract is a valuable, evidence-backed ingredient offering comprehensive protection against environmental aggressors, precisely reducing inflammation and signs of aging, and improving overall skin health for all skin types.

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