Science
Mechanism of Action
The extract's anti-inflammatory and antioxidant actions are primarily mediated by its flavonoid content, including hyperoside, quercetin, isoquercetin, and ellagic acid, which effectively inhibit reactive oxygen and nitrogen compounds. Its antibacterial properties are attributed to naphthoquinones, such as plumbagin. Furthermore, Drosera Rotundifolia Extract actively promotes cellular self-repair by modulating the expression of genes associated with epithelial growth factor receptors, xenobiotic detoxification, and cytokine production, thereby functioning as a comprehensive skin conditioning and tonic agent.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 Reduced acetylcholine-induced contraction by 45% (ex vivo mouse tracheal slices).
- 02 Increased ciliary beat frequency by approximately 10% (0.2 mg/mL dry extract) and 20% (1.0 mg/mL aqueous fraction) (ex vivo murine tracheal epithelial cells).
- 03 Showed antiviral activity against coxsackieviruses A9 and B3 in vitro without cytotoxicity.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Typically extracted using ethanol:water solutions, the resulting dry extract or aqueous fractions are highly soluble in water. Standardization of key active compounds, particularly flavonoids, is important to ensure consistent efficacy and product stability over time.
Safety
Safety Profile
Drosera Rotundifolia Extract has not been formally reviewed by the CIR or SCCS for cosmetic use. However, in vitro studies have indicated no cytotoxicity at concentrations up to 10% (v/v). The 'Drosera rotundifolia whole' is recognized by the FDA's GSRS and is present in various homeopathic/medicinal preparations, suggesting a history of use in other applications. All cosmetic ingredients in the EU undergo rigorous safety assessments regardless of specific ingredient-level reviews.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Drosera Rotundifolia Extract presents as a valuable skincare ingredient, offering robust anti-inflammatory, antioxidant, and cellular repair mechanisms, though its direct clinical efficacy specifically on human skin warrants further dedicated investigation.
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References
Sources