Science
Mechanism of Action
This extract exerts its primary action by scavenging free radicals, a key mechanism for its observed antioxidant properties. Phytochemical analysis reveals a rich composition of compounds such as flavonoids, alkaloids, phenolic compounds, and terpenes, which are known contributors to antioxidant activity. Furthermore, it is hypothesized to function as a humectant, actively drawing moisture from the surrounding air to increase the water content in the skin's superficial layers, thereby offering skin protective benefits.
Research
Clinical Evidence
Low confidenceN/A
Key findings
- 01 An in-vitro study on Dorcoceras uthongensis aqueous extract (DUAE) demonstrated significant free radical scavenging activity, confirming its antioxidant potential across concentrations ranging from 0.195 mg/mL to 12.5 mg/mL (Prajanban et al., 2024).
- 02 Further in-vitro assessment of DUAE showed no cytotoxicity to human T-cell lymphoblasts at concentrations from 7.8 μg/mL to 250 μg/mL, suggesting a favorable safety profile at these tested levels. It also exhibited no toxicity against common Gram-positive (Bacillus subtilis) and Gram-negative (Escherichia coli) bacteria (Prajanban et al., 2024).
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
While in-vitro studies indicate no cytotoxicity to human T-cell lymphoblasts at concentrations up to 250 μg/mL, suggesting a good safety profile at these levels, formal safety assessments by major regulatory bodies such as CIR, SCCS, or FDA are currently unavailable. The ingredient is noted as 'under review' by some cosmetic ingredient databases.
Your Skin
Skin Compatibility
Our Assessment
Verdict
DORCOCERAS HYGROMETRICA LEAF/ROOT EXTRACT shows promising in-vitro antioxidant and humectant properties, but comprehensive safety and human efficacy data are currently insufficient for a definitive assessment in cosmetic formulations.
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References
Sources