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Moumoujus

DONKEY SKIN EXTRACT.

Questionable / ASTRINGENT

Donkey Skin Extract, also known as Ejiao or Donkey-hide Gelatin, is a collagen-rich ingredient derived from donkey hides. It is traditionally valued for its potential to support skin elasticity, provide deep moisturization, and offer anti-aging benefits through its blend of hydrolyzed collagen, amino acids, and bioactive peptides.

Summary

Moisturizing Anti-aging Nourishing Skin elasticity enhancer Anti-inflammatory (preclinical)

Science

Mechanism of Action

This extract primarily functions by enhancing skin moisturization, helping to maintain hydration and prevent dryness for a more supple complexion. Its high collagen content is associated with anti-aging effects, aiming to reduce the appearance of fine lines and wrinkles by supporting skin elasticity and firmness. Additionally, it delivers essential amino acids and nutrients for overall skin health and vitality. Preclinical research suggests anti-inflammatory properties, with findings of inhibiting pro-inflammatory cytokines (IL-6, IL-8, TARC, RANTES) and chemokines, downregulating ICAM-1 and COX-2, and upregulating Filaggrin expression.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Insufficient data available to determine dusting prevalence or thresholds for topical applications. The observed efficacy data is primarily from oral administration in animal models and in vitro studies.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Traditionally prepared by boiling donkey hides, Donkey-hide Gelatin forms a yellowish-brown solid that creates a colloid in aqueous solutions. It transitions to a sol upon heating and a gel upon cooling. It can be dissolved in hot water or alcohol. Specific optimal pH ranges for cosmetic formulation stability are not widely documented.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

There is no official safety assessment for 'Donkey Skin Extract' or 'Donkey-hide Gelatin' as a cosmetic ingredient by CIR or SCCS. Significant concerns exist regarding the sourcing of donkey hides, including potential for spreading infectious diseases due to unregulated transport and improper carcass disposal. Adulteration with gelatins from other animals could introduce unpredictable safety issues, such as bovine spongiform encephalopathy risk, or religious conflicts.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Questionable

While preclinical data suggests potential moisturizing, anti-aging, and anti-inflammatory benefits, the absence of cosmetic safety assessments and significant ethical/sourcing concerns make Donkey Skin Extract a questionable ingredient for precision skincare formulations.

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