Science
Mechanism of Action
This compound functions by significantly reducing the surface tension of liquids, which facilitates efficient cleansing, consistent foam generation, and uniform product dispersion. As an emulsifier, it plays a critical role in stabilizing immiscible liquid phases, such as oil and water, ensuring product homogeneity. Additionally, it acts as an antistatic agent, neutralizing electrical charges on surfaces to prevent static buildup.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has determined that 'trimoniums,' including DODECYLHEXADECYLTRIMONIUM CHLORIDE, are safe for use in cosmetics when formulated to be nonirritating and utilized within specified concentration limits. The Scientific Committee on Consumer Safety (SCCS) authorizes 'Alkyl (C16, C18, C22) trimethylammonium chloride' (a group encompassing this ingredient) as a preservative up to a maximum concentration of 0.1% in cosmetic products. For non-preservative applications, and for related compounds like behentrimonium chloride in leave-on face creams, a maximum total concentration of 0.1% is recommended, subject to case-by-case assessment. It is important to note that concentrated quaternary ammonium compounds are known to cause irritation and corrosion to skin and eyes; studies on related compounds have shown severe irritation at 25% concentration (4 hours contact) and irritation at 8% (3 minutes contact).
Your Skin
Skin Compatibility
Our Assessment
Verdict
DODECYLHEXADECYLTRIMONIUM CHLORIDE is a valuable functional ingredient for improving product texture and stability, requiring precise formulation to adhere to safety concentration limits, typically 0.1% for leave-on products.
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References
Sources