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DODECANENITRILE.

Avoid CAS 2437-25-4 / PERFUMING

Dodecanenitrile is an organic compound primarily employed as a chemical intermediate and solvent. Within cosmetic formulations, its documented role is limited to functioning as a perfuming and fragrance-diffusing agent. It possesses no identified direct biological benefits for the skin, and classifications indicate its potential as a skin irritant.

Fragrance Ingredient Perfuming Agent Fragrance-Diffusing Agent Solvent

Science

Dodecanenitrile does not exhibit a specific mechanism of action on skin biology for therapeutic or intrinsic cosmetic benefits. Its function in formulations is restricted to acting as a perfuming agent and aiding in fragrance diffusion.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

This ingredient demonstrates robust stability across diverse product matrices, including alcoholic lotions, antiperspirants, and various cleaning solutions. Optimal storage involves cool, dry conditions in tightly sealed containers, protected from heat and light. While specific pH ranges for its stability are not detailed, adherence to general cosmetic formulation practices regarding pH maintenance and buffering is recommended to ensure product integrity.


Safety

CIR Status
Not reviewed
Sensitization risk Moderate

While the Research Institute for Fragrance Materials (RIFM) has conducted assessments, the Cosmetic Ingredient Review (CIR) has not formally reviewed Dodecanenitrile, and a definitive 'safe as used' status for cosmetic applications is currently unavailable. The substance is classified under the Globally Harmonized System (GHS) with hazard statement H315: 'Causes skin irritation' and a 'Warning' signal word. The European Chemicals Agency (ECHA) further categorizes it as 'Skin Irrit. 2' for 86.3% of reported instances. There is no specific opinion from the Scientific Committee on Consumer Safety (SCCS), and its presence in the FDA Global Substance Registration System (GSRS) indicates identification without implying specific regulatory approval for cosmetic use.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Dodecanenitrile functions solely as a fragrance and solvent without offering any identified skin benefits, and its established classification as a skin irritant necessitates its exclusion from precision skincare formulations.


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