Science
Mechanism of Action
As a non-ionic, water-soluble dimeric urethane, DISTEARETH-100 IPDI primarily operates by increasing the viscosity of aqueous solutions, thereby modulating the rheological properties of a formulation. This action contributes to a smoother 'slip' upon application and can enhance the body and firmness of the product matrix.
Research
Clinical Evidence
Low confidenceN/A
Transparency
Dusting Analysis
Safety assessments note insufficient data for the use of DISTEARETH-100 IPDI in products where incidental inhalation may occur. Concerns exist for inhalable forms, such as aerosols or fine powders, due to potential toxic impurities, emphasizing the need for cautious formulation in such applications.
The Formula
Formulation
Stability
Exhibits robust stability within acidic pH emulsions and demonstrates compatibility with all major surfactant types, including cationic, anionic, and amphoteric systems.
Synergies
- Cationic Surfactants
- Anionic Surfactants
- Amphoteric Surfactants
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) panel considers DISTEARETH-100 IPDI safe when formulated to be non-irritating. However, there is insufficient data to assess its safety in products that may be incidentally inhaled. Some organizations express heightened concern for inhalable forms due to the potential for toxic impurities. The ingredient is recognized by the FDA's Global Substance Registration System (GSRS), but specific FDA safety status or maximum concentration limits are not detailed.
Your Skin
Skin Compatibility
Our Assessment
Verdict
DISTEARETH-100 IPDI is a valuable non-ionic thickener and rheology modifier, enhancing product texture and feel with low irritancy, though direct skin benefits and safety in inhalable forms require further evaluation.
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References
Sources