Science
Mechanism of Action
This synthetic organic disperse dye functions by dispersing in water for application on hydrophobic substrates such as hair. It adheres to the hair surface through physical interactions, imparting a vibrant blue coloration. Its chemical structure typically includes azo or anthraquinone components.
Research
Clinical Evidence
Medium confidence2%
Transparency
Dusting Analysis
This ingredient is a colorant, not an active compound typically requiring dusting analysis for concentration thresholds or efficacy.
The Formula
Formulation
Stability
Disperse Blue 377 (batch A37372) has demonstrated stability at room temperature for a duration of 1 year. It remained stable in polyethylene glycol 400 solutions for 24 hours at room temperature and for 15 days when stored at 5 ± 3 °C. In dimethylsulfoxide solutions, stability was observed for 8-9 days when maintained at -20 ± 10 °C. Specific stability data within typical hair dye formulations were not provided.
Conflicts
- Amines, components within Disperse Blue 377's structure, may be incompatible with isocyanates, halogenated organics, peroxides, acidic phenols, epoxides, anhydrides, and acid halides.
Safety
Safety Profile
The Scientific Committee on Consumer Safety (SCCS) concluded that the use of Disperse Blue 377 as a non-oxidative hair dye at a maximum concentration of 2.0% in the finished product does not pose a risk to consumer health, provided it is not used in products intended for eyebrows and eyelashes. However, GHS classifications indicate H315 (Causes skin irritation) and H319 (Causes serious eye irritation). SCCS animal studies also noted some irritation to rabbit eyes and well-defined erythema on rabbit skin after patch removal.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Disperse Blue 377 is an effective blue hair dye, deemed safe for its intended use in non-oxidative hair products at up to 2.0%, but its documented potential for skin and eye irritation necessitates careful consideration for any skin-contact cosmetic applications.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources