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DISODIUM PHLORETIN DISULFONATE.

Valuable / SKIN PROTECTING

A highly soluble derivative of phloretin, DISODIUM PHLORETIN DISULFONATE acts as a powerful broad-spectrum antioxidant. It is engineered to enhance the stability and bioavailability of its parent compound, delivering potent brightening and anti-aging benefits to the skin.

Summary

Antioxidant Brightening Anti-inflammatory Melanin Inhibitor Cell Turnover Enhancer Barrier Support Penetration Enhancer Oil Control Skin Cell Regeneration

Science

Mechanism of Action

DISODIUM PHLORETIN DISULFONATE functions as a versatile active ingredient by neutralizing damaging free radicals from environmental stressors like UV radiation and pollution, thereby preventing oxidative damage and premature skin aging. It brightens the complexion and reduces hyperpigmentation through dual actions: inhibiting tyrosinase, the enzyme crucial for melanin synthesis, and accelerating cellular turnover. This ingredient also exhibits anti-inflammatory properties, which help to soothe irritation, minimize redness, and fortify the skin's natural barrier. Furthermore, it enhances the penetration of other active ingredients, regulates oil production, and actively supports skin cell regeneration and barrier repair.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

As a highly soluble derivative engineered for improved bioavailability, there is no indication that DISODIUM PHLORETIN DISULFONATE is commonly formulated at concentrations too low to be effective.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The sulfonation process critical to DISODIUM PHLORETIN DISULFONATE significantly enhances its aqueous solubility and overcomes the photoinstability observed in the parent phloretin. While precise optimal pH for this specific derivative is not directly stated, formulations containing phloretin are typically stable within a pH range of 4 to 10.

Synergies

  • L-ascorbic acid
  • Ferulic acid

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

DISODIUM PHLORETIN DISULFONATE has not been specifically reviewed by regulatory bodies such as CIR, SCCS, or FDA. However, a closely related semisynthetic derivative, phloretin 3',3-disulfonate, demonstrated no adverse reactions when applied topically at 0.1%. The parent compound, phloretin, is generally considered safe for use up to twice daily across most skin types.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

DISODIUM PHLORETIN DISULFONATE is a valuable, multi-functional ingredient that leverages the proven benefits of phloretin in a highly stable and water-soluble form, offering significant antioxidant, brightening, and anti-aging potential with a low risk of irritation.

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