Science
Mechanism of Action
This ingredient functions by reducing the surface tension between diverse substances, thereby facilitating the mixing of water and oils. It achieves cleansing by forming micelles, microscopic structures that entrap dirt, excess oil, and other impurities, allowing them to be readily rinsed from the skin and hair. Beyond cleansing, it offers foaming properties and acts as a conditioning agent.
Research
Clinical Evidence
Medium confidenceEffective as an auxiliary surfactant up to 5%, and as a primary surfactant at higher concentrations, though achieving desired viscosity may require additional polymers. A 1% concentration demonstrated low irritation potential.
Key findings
- 01 A 1% w/w concentration exhibited low irritation to nude mouse skin in a 1-hour test.
- 02 Human Repeat Insult Patch Test (HRIPT) data, evaluating products containing 22% and 30% of the ingredient (tested at 1% and 10% dilutions, respectively), supported its safety, concluding non-irritancy when formulated appropriately.
- 03 A guinea pig study indicated some irritancy at 5%, a common characteristic observed with many surfactants, emphasizing the importance of precise formulation.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
DISODIUM LAUROYL GLUTAMATE is stable within its optimal pH range. The ingredient's form in aqueous solution is pH-dependent, with the disodium glutamate predominating above pH 6.5. In weakly acidic environments (below pH 6.5), a mixture of the acid and salt forms may occur, potentially leading to precipitation of acid crystals and impacting long-term product stability.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that DISODIUM LAUROYL GLUTAMATE is safe for use in cosmetics when products are formulated to be non-irritating. Human studies, including a Human Repeat Insult Patch Test, indicated it was not a dermal irritant. However, the panel noted that most surfactants, including this ingredient at 5% in a guinea pig study, can exhibit some irritancy, hence meticulous formulation is crucial.
Your Skin
Skin Compatibility
Our Assessment
Verdict
DISODIUM LAUROYL GLUTAMATE is a valuable amino acid-based surfactant, offering effective yet gentle cleansing and conditioning properties across all skin types, with a proven low irritation potential when formulated with precision.
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References
Sources
- atamanchemicals.com ↗
- medchemexpress.com ↗
- cir-safety.org ↗
- nbinno.com ↗
- thankmenow.com ↗
- cosmileeurope.eu ↗
- atamankimya.com ↗
- specialchem.com ↗
- incibeauty.com ↗
- nih.gov ↗
- ewg.org ↗
- surfactant.top ↗
- researchgate.net ↗
- icm.edu.pl ↗
- sihaulichemicals.com ↗