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DISODIUM LAURETH-12 SULFOSUCCINATE.

Valuable CAS 58450-52-5 / CLEANSING, SURFACTANT - CLEANSING, SURFACTANT - FOAM BOOSTING, SURFACTANT - HYDROTROPE

Disodium Laureth-12 Sulfosuccinate is a precision-engineered anionic surfactant recognized for its gentle yet highly effective cleansing capabilities. It meticulously reduces surface tension, enabling efficient removal of impurities and promoting luxurious lather in formulations. Its significant molecular size and charge minimize skin penetration, underscoring its mild profile for diverse skin types.

Summary

cleansing agent surfactant foam boosting hydrotrope

Science

Mechanism of Action

This ingredient operates as an anionic surfactant, effectively lowering the surface tension of water. This action facilitates the emulsification and subsequent removal of various impurities, including dirt and oil, from the skin's surface. Additionally, it serves as a foam enhancer, creating a richer lather in cleansing formulations, and acts as a hydrotrope to improve ingredient solubility. Its molecular characteristics, specifically its large size and negative charge, are theorized to prevent its significant absorption into the skin.

Research

Clinical Evidence

High confidence
Effective range 1.68–10%
Optimal

N/A

Key findings

  1. 01 Did not induce skin irritation in dermatitis patients and healthy subjects when applied in aqueous solutions.
  2. 02 Did not induce skin irritation in dermatitis patients and healthy subjects when applied in aqueous solutions.
  3. 03 A trade name mixture at this concentration did not induce clinically significant irritation or allergic contact dermatitis in normal human subjects.
  4. 04 No sensitization observed in guinea pigs from a 25% active matter tradename material, indicating a low sensitization potential.
  5. 05 Was classified as a mild skin irritant in healthy subjects when formulated in a citrate buffer, highlighting the influence of formulation context.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

The ingredient exhibits optimal stability within a pH range of 5.0 to 7.0, with a more precise optimal range of 5.5-6.2 for 10% solutions. As an ester, it is susceptible to hydrolysis in highly alkaline or acidic environments. It maintains stability in hard water conditions. Post-storage, minor cloudiness or crystallization may occur, but these changes are reversible and do not compromise product quality or performance.

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has determined Disodium Laureth-12 Sulfosuccinate to be safe for use in cosmetic and personal care products under current usage patterns and concentrations, provided it is formulated to be non-irritating. The panel concluded that skin penetration is improbable due to its substantial molecular weight and negative electrical charge. Furthermore, it was found to be neither genotoxic, a sensitizer, nor a reproductive or developmental toxicant.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A valuable, mild anionic surfactant, Disodium Laureth-12 Sulfosuccinate provides effective cleansing and foaming with a low risk of irritation or comedogenicity, making it suitable for all skin types when properly formulated.

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