Science
Mechanism of Action
This extract operates by exhibiting powerful intracellular antioxidant activity, effectively reducing reactive oxygen species that contribute to cellular damage. It also provides anti-inflammatory effects by modulating key inflammatory markers such as IL-6 and TNF-α. Rich in phenolic acids, flavonoids, coumarins, hydrolyzable tannins, and tocopherols, it supports skin's natural regenerative processes, as demonstrated by enhanced keratinocyte viability, and offers protective benefits against oxidative stress and premature aging, potentially through elastase and tyrosinase inhibition.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Nut extracts demonstrated remarkable regenerative activity, yielding up to a 28.45% increase in 3D viability within keratinocyte spheroids. The extract also exhibited potent intracellular antioxidant and anti-inflammatory activity, modulating IL-6 and TNF-α.
- 02 Baru seed oil reduced platelet aggregation and lowered the production of reactive oxygen species, contributing to improved vascular function.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The oil extracted from Baru seeds is prone to rapid oxidation upon air exposure, necessitating thoughtful formulation with additional antioxidants and protective packaging to maintain its efficacy and stability.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has not yet reviewed Dipteryx Alata Seed Extract for topical cosmetic use. While a hydroalcoholic extract of the bark demonstrated non-mutagenic properties in Salmonella assays and an oral LD50 of 705 mg/kg in animal studies, this data specifically relates to the bark and not the topical application of the seed extract. Specific safety statuses from CIR, SCCS, or FDA for the seed extract in cosmetics are currently unavailable, suggesting unknown sensitization risk.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Dipteryx Alata Seed Extract is a valuable ingredient for its robust antioxidant, anti-inflammatory, and regenerative properties, offering significant potential for anti-aging and skin protective formulations.
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References
Sources