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DIPEPTIDE-8.

Insufficient Data CAS - / SKIN CONDITIONING

DIPEPTIDE-8 is a specialized peptide recognized for its dual action in enhancing skin regeneration and hydration. It functions as a building block for collagen, visibly diminishing fine lines, while also boosting the skin's natural moisture retention capabilities.

Skin Conditioning Humectant Anti-aging Regenerative Moisturizing Collagen Boosting Elasticity Enhancing

Science

DIPEPTIDE-8 operates by stimulating the skin's intrinsic collagen production, which fortifies structural integrity and enhances elasticity, leading to a reduction in the appearance of wrinkles and fine lines. Its small molecular weight facilitates rapid dermal absorption, where it acts as a precursor for new collagen synthesis. Additionally, it functions as a potent humectant, drawing and binding moisture within the skin, and has been shown to increase hyaluronic acid levels, significantly improving hydration, softness, and resilience against environmental stressors.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH 6 – 8
0 7 14

Stability

This dipeptide is readily soluble in water and maintains stability within a pH range of 6.0 to 8.0, which is optimal for its conformational integrity and sustained efficacy in formulations.


Safety

CIR Status
Not reviewed
Sensitization risk Low

While Dipeptide-8 is mentioned as a food-derived peptide, suggesting a generally safe profile, formal safety assessments by major regulatory bodies such as CIR or SCCS are currently unavailable. Paula's Choice notes it as 'Not rated. No known benefits.', which indicates a lack of official rating rather than an adverse finding.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Insufficient Data

While mechanistically promising for collagen stimulation and hydration across all skin types, comprehensive clinical efficacy data and formal safety assessments are currently limited.


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