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DIPEPTIDE-23.

Valuable / SKIN CONDITIONING

Dipeptide-23, specifically its tranexamoyl-modified form, is a sophisticated synthetic peptide designed for multifaceted skin improvement. Clinically recognized for its exceptional brightening capabilities, it offers a dual-action approach to address hyperpigmentation and enhance overall skin radiance. Beyond its primary lightening effects, this versatile ingredient also contributes to anti-aging, barrier support, and soothing irritated skin.

Skin Brightening Anti-inflammatory Antioxidant Anti-allergic Skin Barrier Support Anti-aging

Science

Tranexamoyl Dipeptide-23 operates through a dual mechanism to combat hyperpigmentation by inhibiting tyrosinase, the key enzyme in melanin synthesis, and by downregulating MITF, which controls melanocyte development and proliferation. Furthermore, it strengthens the skin barrier, provides significant anti-inflammatory and anti-allergic benefits, and supports collagen integrity to diminish the appearance of fine lines and wrinkles.


Research

High confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Stability in formulations is significantly enhanced by its modification with Tranexamic acid. For maximum stability during storage, peptides generally require temperatures below -15 °C, with solutions best stored in aliquots and frozen.

Synergies

  • Tranexamic Acid (for enhanced stability and efficacy)

Safety

CIR Status
Not reviewed
Sensitization risk Low

Cytotoxicity studies affirm Tranexamoyl Dipeptide-23's safety for skincare applications, showing no reported toxicity. Its low irritancy profile further supports its suitability for various skin types.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Tranexamoyl Dipeptide-23 is a highly valuable, clinically supported active ingredient offering superior brightening, anti-aging, and soothing benefits with excellent skin compatibility across all skin types.


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