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DIPEPTIDE-15.

Valuable CAS 556-50-3 / HAIR CONDITIONING, SKIN CONDITIONING

DIPEPTIDE-15 is a versatile peptide esteemed for its skin-conditioning and soothing attributes. It effectively supports skin hydration, refines texture, and aids in mitigating visible irritation and redness, contributing to a more resilient and balanced complexion.

Skin conditioning Moisturizing Soothing Skin barrier strengthening Anti-aging (lines, wrinkles, elasticity) Elastin protection Hair conditioning

Science

Functioning as a signaling peptide, DIPEPTIDE-15 is believed to activate the skin's endogenous repair pathways. This action may visibly reduce fine lines and wrinkles while enhancing skin elasticity and overall complexion. In vitro studies demonstrate its capacity to inhibit MMP-12, a metalloproteinase associated with elastin degradation, by 10%. Furthermore, it contributes to strengthening the skin barrier and promoting a healthy, hydrated dermal state.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No information regarding 'dusting' or ingredient percentages that would suggest it being a 'dusting' ingredient is available in the research data.


The Formula

Solubility
Water
Optimal pH 5 – 7
0 7 14

Stability

DIPEPTIDE-15 is water-soluble and exhibits optimal stability within a pH range of 5.0 to 7.0. Peptides in aqueous solutions are susceptible to degradation via hydrolysis and oxidation. For improved stability, refrigeration (4°C) is recommended for several weeks, or freezing (-20°C to -80°C) for long-term preservation. Lyophilized (freeze-dried) forms are generally more stable than solutions. Maintaining a neutral pH around 7.0 is crucial for preserving peptide integrity.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

DIPEPTIDE-15 is broadly considered safe for use in cosmetic products. However, specific safety assessments by regulatory bodies such as the Cosmetic Ingredient Review (CIR), SCCS, or FDA are not directly available for this particular peptide in the current research, though general assessments for various peptides and proteins exist.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

DIPEPTIDE-15 is a valuable peptide for its hydrating, soothing, and barrier-strengthening properties, offering potential anti-aging benefits supported by in vitro data, making it a beneficial component for skin health.


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