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Moumoujus

DIOSPYROS KAKI LEAF POWDER.

Valuable CAS 91721-74-3 / ABRASIVE

Diospyros Kaki Leaf Powder, derived from persimmon leaves, is a multi-functional botanical ingredient. Rich in flavonoids, tannins, and vitamins, it provides comprehensive skin protection, addresses signs of aging, and promotes a clearer, more radiant complexion.

Summary

Antioxidant Anti-inflammatory Sebum Regulation Anti-Acne Skin Regeneration Anti-aging Skin Brightening Photoprotection Skin Protecting Tonic

Science

Mechanism of Action

This ingredient functions as a potent antioxidant by actively neutralizing free radicals, thereby protecting the skin from environmental stressors and decelerating visible aging. Its anti-inflammatory capabilities stem from inhibiting pathways such as NF-κB and JNK, leading to reduced skin irritation and a calming effect on sensitive or reddened skin. Furthermore, it aids in regulating sebum production and demonstrates antibacterial effects, crucial for managing acne, preventing pore congestion, and reducing pore size. The powder also supports skin regeneration, improving texture and elasticity by inhibiting enzymes like elastase and collagenase, while preventing melanin accumulation through tyrosinase inhibition for a brighter skin tone. It also offers photoprotection against UVA, UVB, and gamma radiation.

Research

Clinical Evidence

Medium confidence
Effective range 2 µg/mL–200 μg/mL%
Optimal

N/A

Key findings

  1. 01 Significantly increased Human Corneal Endothelial Cells (HCECs) viability by approximately 60%.
  2. 02 Exhibited anti-inflammatory potential by inhibiting NF-κB and JNK pathways, blocking T cell activation, and reducing Interleukin-2 mRNA.
  3. 03 Demonstrated 68.73% inhibition of DPPH radical, signifying robust antioxidant activity.
  4. 04 Showed concentration-dependent DPPH radical scavenging capacity, with rates observed between 47.13% and 52.45%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

This ingredient is susceptible to degradation by light and heat. For optimal stability, formulations should be housed in light and air-proof packaging and stored away from direct light and warm environments.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

No specific CIR, SCCS, or FDA safety review is available for Diospyros Kaki Leaf Powder. However, related extracts are generally regarded as safe, classified by SkinSAFE as '100 Free' and 'Irritant Free' with low irritancy. While Diospyros kaki fruit extracts can contain astringent tannins, this concern is significantly less prominent for leaf extract/powder in cosmetic applications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Diospyros Kaki Leaf Powder is a valuable botanical, offering scientifically-backed antioxidant, anti-inflammatory, and regenerative benefits, making it highly compatible and effective across all skin types.

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