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DIOSCOREA VILLOSA ROOT EXTRACT.

Valuable CAS 90147-49-2 / SKIN CONDITIONING

Dioscorea Villosa Root Extract is a botanical active celebrated for its multifaceted benefits, offering potent moisturizing, antioxidant, and anti-inflammatory properties. It works to enhance skin vitality, improve suppleness, and support a more balanced, even-toned complexion.

Emollient Moisturizer/Humectant Antioxidant Anti-inflammatory Soothing Skin barrier support Sebum regulation Melanin inhibition Collagen support

Science

This extract enhances the appearance of dry or damaged skin by reducing flaking and restoring suppleness. Its key active compounds, including steroidal saponins, diosgenin, and flavonoids, contribute to its efficacy. Diosgenin, a steroidal saponin, provides anti-inflammatory and antioxidant benefits, aids in combating collagen degradation, and may stimulate new skin cell growth. Flavonoids deliver robust antioxidant protection against oxidative stress. Saponins further contribute to anti-inflammatory effects by modulating inflammatory pathways and can also enhance the penetration of other active ingredients. The extract's starch and fiber content helps improve skin hydration by forming a protective barrier that retains moisture, reducing trans-epidermal water loss (TEWL). It can also help regulate sebum production, potentially mitigating hormonal acne, and inhibits melanin overproduction to promote a more even skin tone. Additionally, it supports overall skin barrier function and accelerates the skin's natural healing processes.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

No data available to suggest common dusting practices or associated thresholds.


The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Extracts prepared via a specified process are noted to be stable.

Synergies

  • Saponins within the extract can enhance the penetration of other active ingredients, potentially boosting overall formulation efficacy.

Conflicts

  • Potential interaction with estradiol, an estrogen found in some birth control and hormone replacement therapies. Formulators should consider this when developing products for specific user groups.

Safety

CIR Status
Safe as used
Max tested
10%%
Pregnancy
Caution
Sensitization risk Moderate

The CIR Expert Panel considers Dioscorea Villosa Root Extract safe for use in cosmetics when properly formulated. While a 10% dilution was found non-irritating to skin, the undiluted extract was rated 'irritant' to skin and mildly irritating to the eye. Some individuals may experience allergies or sensitivity, therefore a patch test is recommended. Due to potential hormone interactions, it is advised that individuals with conditions like endometriosis, uterine fibroids, or certain forms of cancer, as well as children, pregnant or breastfeeding women, and people with protein S deficiency, avoid products containing this ingredient. The FDA has not assessed wild yam root for safety or efficacy. Manufacturers are advised to ensure pesticide residues do not exceed 40 ppm (with no single residue above 10 ppm) and to ensure diosgenin content is within an expected upper limit of 3.5% for consistent safety profiles. In 2022, the maximum reported use concentration in non-spray moisturizing products was 0.3%.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Dioscorea Villosa Root Extract is a valuable, multi-functional ingredient offering significant hydration, antioxidant protection, and anti-inflammatory benefits, making it beneficial for various skin concerns when formulated thoughtfully and with consideration for specific user contraindications.


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