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DIOCTYLDODECYL LAUROYL GLUTAMATE.

Valuable CAS 82204-94-2 / HAIR CONDITIONING, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SURFACTANT - CLEANSING

DIOCTYLDODECYL LAUROYL GLUTAMATE is a multi-functional lipid with a ceramide-like molecular structure, designed to reinforce the skin's barrier, enhance moisture retention, and provide emollient benefits. It functions as a skin-identical ingredient, supporting epidermal health and resilience.

Emollient Skin-identical ingredient Humectant Barrier Reinforcement Moisture Retention

Science

This ingredient operates by mimicking natural ceramides, forming intercellular lamellar liquid crystals within the skin's lipid matrix. This bilayer structure effectively strengthens the skin barrier, diminishing transepidermal water loss, and fortifying defense against environmental aggressors, allergens, and bacteria. Additionally, it acts as an emollient, softening and smoothing the skin, and boasts humectant properties for superior water binding and hydration.


Research

Insufficient-data confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Safety

CIR Status
Safe with restrictions
Max tested
25.6%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel deems amino acid alkyl amides, including Lauroyl Glutamates, safe for cosmetic use when formulated to be non-irritating. The FDA acknowledges related compounds like Phytosteryl/Octyldodecyl Lauroyl Glutamate as safe, with its use reported in 327 cosmetic products as of 2023. Acute dermal toxicity studies showed an LD50 >2000 mg/kg in rats, and it rarely induces allergic reactions or sensitivity.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

A valuable skin-identical lipid that significantly enhances barrier function, locks in moisture, and provides emollient benefits across all skin types with a low sensitization risk.


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