Science
Mechanism of Action
This ingredient functions by donating hydrogen atoms to free radicals, a critical step in neutralizing them and interrupting chain reactions that lead to oxidative spoilage in formulations. It specifically targets and decomposes hydroperoxides formed during auto-oxidation, and selectively scavenges peroxy radicals. Its high lipophilicity (LogP 10.99) ensures effective interaction with lipid-soluble radicals within skin lipids and product matrices. Furthermore, it can act as an electron donor, regenerating the antioxidant capacity of primary phenolic antioxidants.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
Dimyristyl Thiodipropionate is an active antioxidant ingredient, not typically used as a filler or carrier subject to 'dusting' considerations that would diminish the efficacy of other actives.
The Formula
Formulation
Stability
Possessing a long-chain fatty alcohol structure, Dimyristyl Thiodipropionate demonstrates enhanced solubility across various oil-based formulations. As a secondary thioester antioxidant, it efficiently neutralizes hydroperoxides. Its compatibility with phenolic antioxidants allows for synergistic effects, improving overall stability. The ingredient exhibits characteristics such as low volatility, high melting points, and good compatibility with polymers.
Synergies
- phenolic antioxidants
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel deemed Dimyristyl Thiodipropionate, alongside other thiodipropionic acid derivatives, safe for cosmetic use provided formulations are non-irritating. While a specific maximum safe concentration for this exact compound is not established, studies on the related Dilauryl Thiodipropionate suggest concentrations up to 4% could be irritating, whereas levels of 1% or less (0.05% being standard) are generally considered non-irritating and non-sensitizing. It is permissible in European cosmetics and related compounds are recognized as safe (GRAS) by the FDA for certain uses.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Dimyristyl Thiodipropionate is a valuable ingredient primarily for ensuring the oxidative stability and integrity of sophisticated skincare formulations, protecting other active components.
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