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DIMYRISTOYL GLYCERYL ASCORBATE.

Valuable / ANTIOXIDANT, HUMECTANT, SKIN CONDITIONING

DIMYRISTOYL GLYCERYL ASCORBATE is a highly stable, amphiphilic Vitamin C derivative designed to deliver potent antioxidant protection and comprehensive skin benefits. It actively brightens the complexion, mitigates hyperpigmentation, boosts collagen production, and provides enhanced moisturization.

Summary

Antioxidant Skin Brightening Humectant Collagen Booster Hyperpigmentation Correction Moisturizing Anti-aging

Science

Mechanism of Action

This derivative functions as a powerful antioxidant, effectively neutralizing free radicals and shielding skin from environmental aggressors, including UV damage and oxidative stress. It significantly suppresses melanin synthesis to diminish the appearance of hyperpigmentation and age spots, while simultaneously enhancing collagen production, which improves skin elasticity and firmness for notable anti-aging effects. Additionally, it conditions and moisturizes the skin by acting as a humectant, attracting and retaining essential moisture.

Research

Clinical Evidence

High confidence
Effective range 1–10%
Optimal

N/A

Key findings

  1. 01 Typical use levels for 3-glyceryl ascorbate (1-10%) are observed to provide enhanced moisturizing and antioxidant properties, actively improving the appearance of aged and fragile skin. These concentrations are also utilized in skin-lightening formulations to correct hyperpigmentation and age spots.
  2. 02 Formulations containing 3-Glyceryl Ascorbate (Amitose 3GA) at 5.0% (as ascorbic acid part) demonstrated a stable white appearance in cream bases after 4 weeks at 50°C, affirming its strong oxidative stability.
  3. 03 Concentrated serum formulations with 15.0% 3-Glyceryl Ascorbate (as ascorbic acid part) exhibited no color change over 12 weeks at 50°C, highlighting its superior stability and sustained functional efficacy.
  4. 04 For general biological significance, reputable vitamin C products are commonly formulated within a 10-20% concentration range, with levels exceeding 20% potentially leading to irritation without further increasing efficacy.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 3 – 5.5
0 7 14

Stability

Optimal stability for 3-Glyceryl Ascorbate is noted within a pH range of 3.0 to 5.5, maintaining efficacy in mildly acidic conditions (pH 4.0-5.5). This derivative offers enhanced stability compared to traditional L-Ascorbic Acid, effectively resisting discoloration over time. Ascorbic acid degradation can be influenced by factors such as oxygen, temperature, viscosity, pH, and metal ions.

Synergies

  • Vitamin E

Safety

Safety Profile

CIR Status
Safe as used
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has thoroughly reviewed the category 'Ethers and Esters of Ascorbic Acid', which includes DIMYRISTOYL GLYCERYL ASCORBATE. Their safety assessment concluded that ingredients within this category are safe under current practices of use and concentration.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

DIMYRISTOYL GLYCERYL ASCORBATE is a highly stable and versatile Vitamin C derivative, delivering significant antioxidant, brightening, and moisturizing benefits across all skin types, making it a valuable addition to precision skincare formulations.

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