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Moumoujus

DIMOCARPUS LONGAN FRUIT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Dimocarpus Longan Fruit Extract is a sophisticated botanical ingredient recognized for its comprehensive benefits in skin rejuvenation. Rich in potent antioxidants, it actively combats multiple signs of aging, contributes to a brighter complexion, and provides significant soothing and hydrating properties for a visibly healthier skin barrier.

Summary

Antioxidant Skin-Conditioning Anti-aging Skin Brightening Soothing Moisturizing Collagen Protection Hyaluronic Acid Preservation

Science

Mechanism of Action

This extract operates through several intricate mechanisms to enhance skin health. Functioning as a potent antioxidant, it leverages its rich profile of polyphenols, flavonoids, gallic acid, corilagin, and ellagic acid to effectively scavenge free radicals, thereby mitigating oxidative stress and preventing photoaging. Its anti-aging efficacy is significantly driven by inhibiting collagenase and Matrix Metalloproteinase-1 (MMP-1), enzymes notorious for accelerating collagen degradation. The extract also contributes to skin brightening by reducing melanin production in a dose-dependent manner. Furthermore, it demonstrates anti-inflammatory and skin-soothing actions through the inhibition of inflammatory cytokines such as IL-6 and TNF-α. It also helps maintain skin hydration and elasticity by inhibiting hyaluronidase activity, which preserves endogenous hyaluronic acid levels, while its polysaccharide content facilitates deep skin moisturization by binding to water molecules.

Research

Clinical Evidence

High confidence
Effective range 0.5–2.5%
Optimal

N/A

Key findings

  1. 01 Demonstrated highly potent anti-aging properties, including a significant reduction in collagenase activity, dose-dependent skin whitening effects, and notable skin-soothing benefits. Skin tolerance was confirmed in rigorous in vitro irritation/corrosion assays and human patch tests.
  2. 02 Exhibited potent inhibition of Matrix Metalloproteinase-1 (MMP-1) with an IC50 of 21.7 ± 5.4 µg/mL and hyaluronidase (oleanolic acid equivalent = 0.44 ± 0.03 g per g extract). This formulation showed no irritation in HET-CAM tests.
  3. 03 Successfully formulated into a stable cream, demonstrating robust antioxidant properties with an IC50 of 23.5 µg/ml for radical scavenging activity.
  4. 04 Showed significant inhibitory activities against the secretion of pro-inflammatory markers IL-6 and TNF-α in RAW 264.7 macrophage cells, without inducing cytotoxicity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH 5.5 – 5.5
0 7 14

Stability

A lamellar liquid crystal formulation containing 0.5% w/w ethyl acetate extract of black Dimocarpus longan seed demonstrated good stability following heating-cooling cycles at its optimal pH of 5.5. The overall stability of cream formulations containing the extract can also be influenced by the choice of emulsifying agent.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Comprehensive skin corrosion and irritation tests, performed according to OECD guidelines, alongside patch tests aligned with ICDRG guidelines, have consistently confirmed the skin's excellent tolerance to Dimocarpus Longan Fruit Extract. In vitro HET-CAM tests, an irritation assessment method, also revealed no irritation signs for black Dimocarpus longan seed extracts. In the European Union, cosmetic products incorporating this ingredient are subject to rigorous safety assessments by qualified scientific experts.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Dimocarpus Longan Fruit Extract is a valuable ingredient, offering proven multi-faceted benefits in anti-aging, antioxidant defense, brightening, and soothing, with a good safety profile for a wide range of skin types.

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