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Moumoujus

DIMETHYL SULFONE.

Valuable CAS 67-71-0 / SOLVENT, VISCOSITY CONTROLLING

Dimethyl Sulfone, commonly known as MSM, is a naturally occurring organic sulfur compound. It plays a crucial role in maintaining skin integrity and health, offering significant anti-inflammatory, antioxidant, and structural support benefits.

Summary

Solvent Viscosity Controlling Anti-inflammatory Antioxidant Skin-Conditioning Sebum-Regulating Exfoliant

Science

Mechanism of Action

MSM delivers bioavailable sulfur, a vital component for the synthesis of collagen and elastin, foundational proteins for skin structure and elasticity. It enhances cell membrane permeability, facilitating efficient nutrient uptake and waste elimination. Furthermore, MSM supports healthy keratin production, contributing to smoother, firmer skin. As a potent antioxidant, it neutralizes free radicals, mitigating damage from environmental aggressors. Its well-documented anti-inflammatory properties help soothe redness and irritation. MSM actively promotes collagen synthesis, thereby improving skin elasticity and firmness. It may also modulate sebum production and possesses mild antibacterial qualities beneficial for acne-prone skin. At concentrations exceeding 3%, Dimethyl Sulfone also functions as a gentle exfoliant, while generally enhancing the deeper penetration of other active ingredients.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Topical MSM demonstrates anti-inflammatory, anti-itch, and skin-softening effects, comparable to urea and lanolin.
  2. 02 Clinical studies indicate significant improvements in the appearance of wrinkles, skin firmness, and elasticity.
  3. 03 A 2015 scientific investigation reported enhanced facial wrinkle severity, tone, texture, and firmness with MSM application.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH 3 – 7
0 7 14

Stability

Stable within a pH range of 3 to 7. It is readily soluble in water, glycols, and ethanol, and can be incorporated into cream or gel bases. While heating to 70-80°C can aid solubility, sustained temperatures above 60°C are best avoided for optimal stability.

Conflicts

  • Vitamin C (potential to accelerate oxidation and premature degradation)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

Recognized by the FDA as Generally Recognized As Safe (GRAS) and generally considered safe and effective by EU and other regulatory bodies for cosmetic use. While largely well-tolerated, some individuals with extremely sensitive skin might experience mild reactions like itching or redness; a sensitivity test is advisable. It's crucial to distinguish Dimethyl Sulfone from Dimethyl Sulfoxide (DMSO); high concentrations of DMSO (above 50%) can cause significant skin irritation, a risk not associated with Dimethyl Sulfone.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Dimethyl Sulfone is a valuable multi-functional ingredient, offering significant anti-inflammatory, antioxidant, and anti-aging benefits suitable for all skin types, with established safety and good formulation flexibility.

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