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DIMETHYL ISOPROPANOLAMINE.

Valuable CAS 108-16-7 / BUFFERING

Dimethyl Isopropanolamine is a critical formulation additive, primarily functioning as an alkaline pH adjuster and buffering agent to maintain product stability. It also aids in emulsification and dispersion, ensuring uniform ingredient distribution within precision skincare systems.

Summary

pH adjuster Buffering agent Neutralizing agent Emulsifier Dispersing agent Wetting aid

Science

Mechanism of Action

This alkaline compound precisely modifies the acidity or alkalinity of a cosmetic formulation, achieving and maintaining a desired pH range vital for ingredient stability and product efficacy. Beyond pH regulation, it acts as an emulsifier, stabilizing oil-in-water or water-in-oil mixtures, and a dispersing agent, ensuring even distribution of insoluble components.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Dimethyl Isopropanolamine serves specific functional roles as a pH adjuster and emulsifier, essential for product stability and texture. Its inclusion is typically deliberate for formulation integrity, rather than as a 'dusted' ingredient added without clear functional intent or specific concentration.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Possessing a pH of 12.1 at 20 °C in its pure form, Dimethyl Isopropanolamine is highly alkaline and used for maintaining alkaline pH or neutralizing acidic components. It is sensitive to air and should be stored under a dry inert gas to preserve stability.

Conflicts

  • N-nitrosating agents (potential formation of harmful nitrosamines)
  • Oxidizing agents
  • Air (sensitivity)

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
1%
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Dimethyl Isopropanolamine, as part of the Mixed Isopropanolamines group, safe for cosmetic use within current practices and concentrations, with a maximum reported use of 1% in some applications. A crucial restriction is that it must not be used in formulations containing N-nitrosating agents, as this combination can lead to the generation of potentially harmful nitrosamines. The FDA does not pre-approve individual cosmetic ingredients, emphasizing that cosmetic products must be safe when used as directed.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Dimethyl Isopropanolamine is a valuable functional ingredient for optimizing product stability and texture through precise pH adjustment and emulsification, provided its use adheres to safety restrictions regarding N-nitrosating agents.

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