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DIISOSTEARYL LAUROYL GLUTAMATE.

Valuable CAS - / HAIR CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Diisostearyl Lauroyl Glutamate is a sophisticated emollient and non-ionic surfactant designed to enhance skin barrier function. Its unique ceramide-like structure helps to fortify the skin's natural defenses, effectively locking in moisture and protecting against environmental stressors. This ingredient delivers softening and conditioning benefits without leaving an oily residue.

Summary

Emollient Hair Conditioning Skin Barrier Strengthening Moisturizing Softening

Science

Mechanism of Action

This ingredient functions as a non-ionic surfactant and emollient, closely mimicking skin lipids to form intercellular lamellar liquid crystals with a bilayer membrane structure. This ceramide-like molecular architecture is crucial for strengthening the skin's natural barrier, thereby sealing moisture within the skin and shielding it from external aggressors. Additionally, it offers anti-ion and anti-static properties, contributing to improved formulation texture, pigment dispersion, and emulsion stability.

Research

Clinical Evidence

Medium confidence
Effective range ≤25.6%
Optimal

N/A

Key findings

  1. 01 Related phytosteryl glutamates, such as Phytosteryl/Behenyl/Octyldodecyl Lauroyl Glutamate and Phytosteryl/Octyldodecyl Lauroyl Glutamate, are safely utilized in leave-on products, including rouges, at concentrations up to 25.6%, and up to 25% in lipsticks.
  2. 02 Manufacturer-conducted tests suggest that a related compound, Phytosteryl/Octyldodecyl Lauroyl Glutamate, demonstrates superior efficacy compared to petrolatum in supporting the recovery of compromised skin and ameliorating rough skin textures.

Transparency

Dusting Analysis

Not commonly dusted

No specific data regarding dusting characteristics is available for Diisostearyl Lauroyl Glutamate in the provided research.

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Diisostearyl Lauroyl Glutamate exhibits stability across a relatively broad pH range. While no specific optimal pH range is provided for this exact ingredient, a related compound, Sodium Lauroyl Glutamate, achieves optimal stability and foaming performance at pH 6.0-6.5, with an overall optimal formulating range of pH 4.0-10.0.

Safety

Safety Profile

CIR Status
Safe as used
Max tested
25.6%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has assessed a broader category of 'amino acid alkyl amides,' which includes lauroyl glutamates, concluding they are safe for cosmetic use within current practices and concentrations, provided they are formulated to be non-irritating. Specifically, related phytosteryl glutamates, such as Phytosteryl/Octyldodecyl Lauroyl Glutamate, have been deemed safe as used, with maximum reported concentrations up to 25.6% in leave-on products. FDA VCRP data from 2023 indicates the use of Phytosteryl/Octyldodecyl Lauroyl Glutamate in 327 cosmetic products.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Diisostearyl Lauroyl Glutamate is a valuable ingredient, leveraging its ceramide-like structure to strengthen the skin barrier and provide significant moisturizing and softening benefits across all skin types, with a strong safety profile for related compounds.

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