Science
Mechanism of Action
This ingredient functions primarily as an emollient, bestowing comfort, softness, and a visually radiant quality to the skin, while also assisting in oil balance. It contributes to strengthening the skin's protective barrier, thereby aiding in moisture retention and safeguarding against external stressors. As a solvent, Diisopropyl Sebacate enhances the efficacy and uniform distribution of other active components in a formulation. Furthermore, it acts as a plasticizer, improving product texture and spreadability without imparting a greasy residue, and contributes to a lightweight, non-greasy feel with efficient skin penetration as a conditioning agent.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Typical usage levels, ranging from 1% to 10% in skincare products, are shown to improve spreadability, reduce greasiness, and enhance overall skin feel, contributing to a more pleasant user experience.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Diisopropyl Sebacate exhibits good thermal stability and has a reported neutral pH of 7.0.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel concluded that Diisopropyl Sebacate is safe for use in cosmetic products at concentrations up to 10%. While generally considered non-irritating and non-comedogenic, a mouse model study indicated that Diisopropyl Sebacate facilitated skin sensitization to fluorescein isothiocyanate via TRPA1 activation. Under U.S. law, cosmetic ingredients, excluding color additives, do not require FDA pre-market approval.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Diisopropyl Sebacate is a valuable ingredient that significantly improves cosmetic elegance and skin comfort through its emollient, conditioning, and solvent properties, with a low risk of irritation for most skin types within safe usage concentrations.
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