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DIISOPROPYL ADIPATE.

Valuable CAS 6938-94-9 / FRAGRANCE, PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Diisopropyl Adipate is a lightweight, non-occlusive emollient and skin-conditioning agent that enhances skin softness and smoothness. It optimizes product texture and spreadability while serving as a versatile solvent, improving the dispersion and delivery of active ingredients, especially UV filters.

Summary

emollient masking plasticiser skin conditioning solvent

Science

Mechanism of Action

Diisopropyl Adipate acts as a lubricant on the skin's surface, imparting a soft and smooth appearance. It functions as a lightweight, non-greasy emollient, helping to reduce transepidermal water loss and maintain skin hydration. By forming a rapidly absorbed film, it provides a light, dry-touch feel. Additionally, it serves as an effective solvent, increasing the solubility and dispersion of various ingredients, including oil-soluble active compounds and UV filters, thereby enhancing their delivery to the skin. It also contributes to improved product texture and spreadability.

Research

Clinical Evidence

High confidence
Effective range 0.1–25%
Optimal

N/A

Key findings

  1. 01 Diisopropyl Adipate is recommended for use across a concentration range of 0.1% to 25%, depending on its functional role within the formulation, such as an emollient, plasticizer, or solvent for active ingredients and UV filters.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Diisopropyl Adipate demonstrates excellent chemical stability, contributing to a prolonged product shelf-life and consistent performance across a broad pH range. It exhibits good compatibility with a variety of cosmetic ingredients, including silicones and other oils. It is frequently utilized in hydro-alcoholic formulations and acts as a solubilizer for lipophilic media, stabilizing solid organic UV filters and potentially assisting with Avobenzone photostabilization.

Synergies

  • Silicones
  • Oils
  • Active compounds
  • Hydro-alcoholic formulations
  • Solid organic UV filters (for stabilization)
  • Avobenzone (for photostabilization)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
8%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Diisopropyl Adipate safe for cosmetic and personal care products at concentrations up to 8.0%, reaffirming this conclusion in 2010. It is regarded as a non-toxic and non-carcinogenic ingredient with low acute oral and dermal toxicity. While undiluted forms may cause very mild, transient eye or minimal primary dermal irritation, formulations containing up to 20% consistently resulted in minimal to mild irritation, no sensitization, and no photosensitization. It is permitted for use in cosmetics in Europe and is regulated by the FDA for specific indirect food additive and topical pharmaceutical applications.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Diisopropyl Adipate is a valuable, safe, and versatile ingredient that significantly enhances skin feel and product performance, particularly in improving active ingredient delivery and UV filter stability.

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