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DIISOBUTYL MALEATE.

Avoid CAS 14234-82-3 / PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT

Diisobutyl Maleate is a diester typically employed for its skin conditioning and emollient properties, contributing to skin smoothness. While chemically structured to potentially yield beneficial components like malic acid upon metabolism, its GHS classifications highlight a significant risk for skin irritation and allergic sensitization, making its use in sensitive formulations particularly challenging.

Skin Conditioning Agent Emollient Plasticizer

Science

This diester functions primarily as a skin conditioning agent and emollient, contributing to a softer skin feel. Upon application, it may undergo enzymatic hydrolysis by skin esterases, breaking down into a monoester, malic acid, and the corresponding alcohol. Research on the closely related isomer, Dibutyl Maleate, suggests additional benefits such as enhancing UV filtration and improving hair flexibility and gloss.


Research

Low confidence
Effective range N/A
Optimal

N/A


Transparency

Not commonly dusted

The Formula

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

The compound is unstable in the presence of heat, acids, or bases, which can lead to its transposition into fumaric acid dialkyl ester.

Conflicts

  • oxidizing agents
  • strong bases

Safety

CIR Status
Safe with restrictions
Sensitization risk High

While the broader 'dialkyl malates' group, which includes related isomers, has been deemed safe for cosmetic use by the CIR Expert Panel, specific GHS classifications for Diisobutyl Maleate indicate it 'Causes skin irritation' and 'May cause an allergic skin reaction'. Animal studies on a closely related isomer suggest a potential to aggravate contact dermatitis through a skin sensitization process, indicating a notable risk for sensitive individuals.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy High
Comedogenicity Unknown

Our Assessment

Avoid

Given its high propensity for causing skin irritation and allergic reactions, combined with an absence of specific clinical efficacy data for this compound, Diisobutyl Maleate is deemed unsuitable for inclusion in Moumoujus's precision skincare formulations.


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