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Moumoujus

DIISOBUTYL ADIPATE.

Valuable CAS 141-04-8 / FRAGRANCE, PLASTICISER, SKIN CONDITIONING, SKIN CONDITIONING - EMOLLIENT, SOLVENT

Diisobutyl Adipate is a lightweight ester that serves as an effective emollient and solvent in skincare formulations. It contributes to a soft, smooth skin texture while also enhancing product spreadability and dissolving other key ingredients.

Summary

Emollient Solvent

Science

Mechanism of Action

As an emollient, Diisobutyl Adipate forms a fine, protective layer on the skin's surface, functioning as a lubricant to impart a soft and smooth appearance while aiding in moisture retention. Its solvent properties enable it to dissolve various cosmetic ingredients, including UV filters in sunscreens, thereby improving overall product texture and spreadability, resulting in an elegant and non-tacky skin feel.

Research

Clinical Evidence

High confidence
Effective range 0.005–8%
Optimal

N/A

Key findings

  1. 01 Clinical research indicates Diisobutyl Adipate is safely used in cosmetic formulations at concentrations ranging from 0.005% to 8%, suitable for both leave-on and rinse-off applications.
  2. 02 Animal dermal irritation tests and human clinical patch tests demonstrated no to minimal irritation, even when the substance was applied undiluted.
  3. 03 A human Draize test involving 20 volunteers showed no indication of sensitization.
  4. 04 Studies on structurally similar compounds, such as Dibutyl Adipate, have shown no comedogenic effects.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Exhibits excellent thermal and hydrolytic stability, ensuring its integrity under normal processing and storage conditions.

Synergies

  • UV filters (enhanced solubilization)

Conflicts

  • strong oxidizing agents

Safety

Safety Profile

CIR Status
Safe as used
Max tested
8%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Diisobutyl Adipate is safe for use as a cosmetic ingredient, a finding often referenced alongside assessments for Dibutyl Adipate. It is associated with low concerns for cancer, allergies, immunotoxicity, and developmental and reproductive toxicity by reputable safety databases. Furthermore, the FDA lists Diisobutyl Adipate as a food contact substance.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

Diisobutyl Adipate is a valuable emollient and solvent, offering enhanced product texture, optimal spreadability, and a non-greasy feel, supported by a strong safety profile and broad compatibility for all skin types.

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