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DIHYDROQUERCETIN.

Valuable CAS 480-18-2 / ANTIOXIDANT

Dihydroquercetin is a potent antioxidant derived from plants, known for its ability to neutralize free radicals and protect skin from environmental damage. It helps improve skin viscoelasticity and supports overall skin health, making it valuable for anti-aging and protective formulations.

Antioxidant Anti-inflammatory Soothing Anti-acne

Science

It acts as a powerful antioxidant, protecting cells and collagen from oxidative stress and degradation by inhibiting MMP-1. Additionally, it possesses anti-inflammatory and antimicrobial properties, modulating inflammatory pathways and fighting acne-causing bacteria.


Research

High confidence
Effective range 0.01–3%
Optimal

0.1%

Key findings

  1. 01 A 3% Taxifolin (Dihydroquercetin) cream improved skin viscoelasticity and was proven to be non-irritant in a study with 97 Caucasian women.
  2. 02 A 3% Stizolophus balsamita extract cream, containing taxifolin, reduced hyperpigmentation, erythema, and elevated pH in adult skin.

Transparency

Not commonly dusted

No specific data on dusting is available. Its low water solubility may present formulation challenges, requiring specialized delivery systems for optimal efficacy.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Dihydroquercetin has low water solubility, requiring ethanol or surfactants for dissolution and delivery systems like nanoparticles for effective topical delivery. It should be mixed in the last step, avoiding heat, and can act as an antioxidant preservative.


Safety

CIR Status
Not reviewed
Max tested
3%
Sensitization risk Low

Dihydroquercetin has a high safety profile, recognized as GRAS by the FDA for food use. It is registered in INCI and not listed as a prohibited or restricted cosmetic substance.


Your Skin

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

Dihydroquercetin is a highly beneficial ingredient, offering significant antioxidant, anti-inflammatory, and anti-aging properties with a strong safety profile and broad skin compatibility.


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