Science
Mechanism of Action
This ingredient exerts its effects by neutralizing free radicals and inhibiting lipid peroxidation, offering significant antioxidant protection. It also possesses anti-inflammatory properties and acts as a RAGE inhibitor, which delays cellular senescence and promotes collagen synthesis.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 Alleviates AGE-induced cellular senescence and promotes cell proliferation in 3D skin models.
- 02 Inhibits UVA-induced ROS generation, mitigating oxidative damage and reducing inflammatory factors.
- 03 Enhances skin elasticity and preserves collagen levels, demonstrating anti-aging effects.
Transparency
Dusting Analysis
While natural Dihydromyricetin has low water solubility, specialized formulation techniques allow for water-soluble forms, ensuring it can be effectively delivered without commonly being dusted in well-formulated products.
The Formula
Formulation
Stability
Dihydromyricetin is most stable in acidic conditions (pH 1.0-5.0) and degrades in alkaline solutions. Its stability is compromised by metal ions and excessive heat.
Conflicts
- Metal ions (Fe³⁺, Al³⁺, Cu²⁺)
- Strong alkaline environments (pH > 6.0)
Safety
Safety Profile
Generally considered safe for topical application with low potential for acute and repeated dose toxicity at typical use concentrations. No discernible cytotoxicity was observed in vitro.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A valuable multi-functional ingredient that offers strong antioxidant, anti-aging, and anti-inflammatory benefits, compatible with most skin types.
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References
Sources