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Moumoujus

DIHEXYL FUMARATE.

Optional CAS 19139-31-2 / PERFUMING

Dihexyl Fumarate is an oil-soluble fumarate ester primarily functioning as an emollient and perfuming agent in cosmetic formulations. It is also listed by the FDA for use in food contact materials.

Summary

Emollient Perfuming

Science

Mechanism of Action

As a fumarate ester, it may influence pro-inflammatory pathways by modulating the intracellular redox system and signaling proteins like Nrf2 and NF-κB, similar to pharmaceutical FAEs. This could potentially lead to anti-inflammatory and immunomodulatory effects.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Oil
Optimal pH N/A
0 7 14

Stability

Dihexyl Fumarate is stable under standard conditions but will hydrolyze in the presence of water or under acidic or basic conditions.

Conflicts

  • water (due to hydrolysis)
  • acidic conditions (due to hydrolysis)
  • basic conditions (due to hydrolysis)

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Unknown

While FDA lists 'HEXYL FUMARATE' for food contact and fumaric acid is GRAS, no specific CIR or SCCS safety review exists for its cosmetic use. Safety data indicates it may cause irritation upon contact with skin or eyes.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Optional

Functions as an emollient and perfuming agent, but its potential deeper anti-inflammatory mechanisms are extrapolated from related compounds and lack direct skincare efficacy data.

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