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Moumoujus

DIETHYL MALATE.

Valuable CAS 7554-12-3 / PERFUMING

Diethyl malate is a malate ester primarily recognized for its ability to enhance the penetration of other active ingredients in topical skincare formulations. It additionally functions as a metabolite.

Summary

Penetration Enhancer

Science

Mechanism of Action

As a malate ester, diethyl malate functions as a metabolite within the skin. Its key mechanism in formulations involves improving the transdermal delivery of co-applied compounds, thereby augmenting their efficacy.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Both
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

This ingredient does not meet GHS hazard criteria. The JECFA concluded no safety concerns at current intake levels when used as a flavoring agent, and it holds FDA clearance for indirect food contact.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A valuable penetration enhancer that can improve the delivery of active ingredients in skincare formulations.

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