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DICTYOPHORA INDUSIATA FRUITING BODY EXTRACT.

Valuable CAS - / ANTIMICROBIAL, HUMECTANT, SKIN CONDITIONING

This multi-functional extract from the Dictyophora indusiata mushroom offers potent antioxidant and anti-inflammatory benefits, while promoting collagen health and hydration for revitalized skin.

Antioxidant Anti-inflammatory Humectant Skin-Conditioning Antimicrobial Collagen Stimulating

Science

It effectively scavenges free radicals and suppresses pro-inflammatory mediators like NO, TNF-α, IL-1β, and IL-6. Additionally, it inhibits MMP-2 activity to support collagen, acts as a humectant, and possesses antimicrobial properties.


Research

High confidence
Effective range ≥2 mg/mL%
Optimal

N/A

Key findings

  1. 01 An aqueous extract at 2 mg/mL demonstrated high scavenging of DPPH (97.35%), hydroxyl (52.28%), and superoxide anion (48.64%) radicals.
  2. 02 A core extract significantly suppressed nitric oxide secretion to 0.06 µmol/L (vs. 0.12 µmol/L for diclofenac) and inhibited MMP-2 activity by 41.33%.
  3. 03 Isolated compounds exhibited anti-inflammatory effects by inhibiting TNF-α (IC50: 11.9 μM), IL-6 (IC50: 13.53 μM), and IL-1β (IC50: 23.9 μM).

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

While an optimal pH of 5.25 was noted for polysaccharide extraction, no specific pH range for cosmetic formulation stability has been identified.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

Listed on COSMILE Europe and widely consumed as food, animal studies showed no toxicity at high doses (up to 1200 mg/kg) over two months.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

With robust antioxidant and anti-inflammatory properties, coupled with collagen-boosting and hydrating effects, this extract offers significant benefits for diverse skincare formulations.


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