Science
Mechanism of Action
It significantly reduces inflammation by inhibiting nitric oxide, TNF-α, and IL-6 production, and supports collagen by suppressing MMP-2 activity. Furthermore, it provides robust antioxidant protection through free radical scavenging, enhancing overall skin integrity and repair.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 CW extract (68.761 ± 0.010 mg/g catechin) significantly suppressed nitric oxide secretion (0.06 ± 0.02 µmol/L) from macrophage cells, comparable to diclofenac.
- 02 Inhibited MMP-2 activity by 41.33 ± 9.44% (CW extract) and up to 59.63 ± 8.31% (PGW extract), promoting collagen stimulation.
- 03 Specific compounds isolated from the extract potently inhibited NO (10.86 µM), TNF-α (11.9 µM), and IL-6 (13.53 µM) production, demonstrating targeted anti-inflammatory effects.
- 04 UAE water extract exhibited strong antioxidant activity with an IC50 of 5.68 ± 0.09 mg/mL in the ABTS assay.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The extract powder is prone to moisture absorption, indicating hygroscopic properties that require careful handling during formulation.
Safety
Safety Profile
No regulatory safety assessments by CIR, SCCS, or FDA were found. Supplier specifications indicate purity from pesticides and heavy metals (e.g., Pb < 2.0 ppm).
Your Skin
Skin Compatibility
Our Assessment
Verdict
Dictyophora indusiata Extract is a valuable, multi-functional ingredient providing potent anti-inflammatory, antioxidant, and collagen-protective benefits for enhanced skin health, particularly suitable for sensitive and normal skin.
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